RAB32 and PPP3R2

Data Source:
BioGRID (two hybrid)

		RAB32	PPP3R2
Description		RAB32, member RAS oncogene family	protein phosphatase 3 regulatory subunit B, beta
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Early Endosome Endoplasmic Reticulum Trans-Golgi Network Cytosol Endomembrane System Membrane Phagocytic Vesicle Membrane Early Endosome Lumen Melanosome Membrane Melanosome Mitochondria-associated Endoplasmic Reticulum Membrane Phagocytic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding GTP-dependent Protein Binding AP-2 Adaptor Complex Binding AP-1 Adaptor Complex Binding AP-3 Adaptor Complex Binding BLOC-2 Complex Binding	Calcium Ion Binding Protein Binding Calcium-dependent Protein Serine/threonine Phosphatase Regulator Activity
	Biological Process	Intracellular Protein Transport Mitochondrion Organization Vesicle-mediated Transport Antigen Processing And Presentation Melanosome Organization Endosome To Melanosome Transport Protein Localization To Membrane Phagosome Maturation Melanosome Assembly	Regulation Of Phosphoprotein Phosphatase Activity
Pathways		RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs			Cyclosporine Voclosporin
Diseases
GWAS		Leprosy ( 27976721 25642632 22019778) Metabolite levels ( 23823483)
Interacting Genes		5 interacting genes: CHM DDIT4L LRMDA PPP3R2 PRKAR2A	19 interacting genes: APC AURKA BUB1 CCND1 CD14 DLC1 DYNLL1 FBXW7 KRT34 MLH3 MSH2 PDGFRL PPP3CA PTPN12 PTPRJ RAB32 SMAD4 TBC1D10C TFCP2
Entrez ID		10981	5535
HPRD ID		06700	10164
Ensembl ID		ENSG00000118508	ENSG00000188386
Uniprot IDs		Q13637	Q96LZ3
PDB IDs		4CYM 4CZ2 5OEC 5OED 6FF8
Enriched GO Terms of Interacting Partners?
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