TMED2 and GORASP1

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		TMED2	GORASP1
Description		transmembrane p24 trafficking protein 2	golgi reassembly stacking protein 1
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GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPII-coated ER To Golgi Transport Vesicle COPI-coated Vesicle COPI-coated Vesicle Membrane Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Zymogen Granule Membrane Intracellular Membrane-bounded Organelle	Golgi Membrane Golgi Apparatus Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Neural Tube Closure Maternal Placenta Development Heart Looping Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Organization Positive Regulation Of Gene Expression Somite Rostral/caudal Axis Specification Negative Regulation Of GTPase Activity Multicellular Organism Growth Vesicle Cargo Loading Post-anal Tail Morphogenesis PERK-mediated Unfolded Protein Response COPI Coating Of Golgi Vesicle COPII Vesicle Coating Labyrinthine Layer Blood Vessel Development Protein Localization To Plasma Membrane Endoplasmic Reticulum Membrane Organization Negative Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation Regulation Of SREBP Signaling Pathway	Protein N-linked Glycosylation Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport COPII Vesicle Coating Negative Regulation Of Dendrite Morphogenesis Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways		Pre-NOTCH Processing in Golgi COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Educational attainment ( 25201988) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Social communication problems ( 24564958)
Interacting Genes		9 interacting genes: AKT2 ARF1 ARFGAP1 COPA GOLGA2 GORASP1 GORASP2 SEC23B TMED10	17 interacting genes: AGPS CASP3 CASP7 CDK1 GOLGA2 HIPK3 LONRF1 MAPK6 NEFL PLK1 PRKD2 RPS6KA1 SCRN1 TGFA TMED2 TMED3 TRAF4
Entrez ID		10959	64689
HPRD ID		17984	06038
Ensembl ID		ENSG00000086598	ENSG00000114745
Uniprot IDs		Q15363 Q6FHT8	A0A024R2U5 B3KPY8 B4E1H8 Q9BQQ3
PDB IDs		5AZW	4REY 6G8T 6G8W
Enriched GO Terms of Interacting Partners?
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