SMPDL3A and BRINP1

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		SMPDL3A	BRINP1
Description		sphingomyelin phosphodiesterase acid like 3A	BMP/retinoic acid inducible neural specific 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Extracellular Exosome	Cytoplasm Endoplasmic Reticulum Dendrite Neuronal Cell Body
	Molecular Function	Sphingomyelin Phosphodiesterase Activity Protein Binding Phosphoric Diester Hydrolase Activity Zinc Ion Binding	Protein Binding
	Biological Process	Sphingomyelin Catabolic Process Nucleoside Triphosphate Catabolic Process	Behavioral Fear Response Cell Cycle Arrest Short-term Memory Cell Death Social Behavior Exploration Behavior Maternal Behavior Positive Regulation Of Neuron Differentiation Negative Regulation Of Cell Cycle Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Neurogenesis Cellular Response To Retinoic Acid Vocalization Behavior
Pathways
Drugs
Diseases
GWAS		Blood protein levels ( 30072576 29875488 28240269) Malaria ( 31844061)	Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) Coffee consumption ( 31046077) Emphysema annual change measurement in smokers (adjusted lung density) ( 31324189) Hip circumference ( 28552196) Household income (MTAG) ( 31844048) Impulsivity (motor) ( 30718321) Manganese levels ( 26025379) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Smoking status (ever vs never smokers) ( 30643258) Urinary sodium excretion ( 31409800)
Interacting Genes		1 interacting genes: BRINP1	5 interacting genes: CCND1 HDAC3 MDM2 RAC1 SMPDL3A
Entrez ID		10924	1620
HPRD ID		10244	04181
Ensembl ID		ENSG00000172594	ENSG00000078725
Uniprot IDs		Q92484	O60477
PDB IDs		5EBB 5EBE
Enriched GO Terms of Interacting Partners?
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