GADD45G and PDIA4

Data Source:
BioGRID (two hybrid)

		GADD45G	PDIA4
Description		growth arrest and DNA damage inducible gamma	protein disulfide isomerase family A member 4
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GO Annotations	Cellular Component	Nucleus Cytoplasm	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Cell Surface Melanosome
	Molecular Function	Protein Binding	RNA Binding Protein Disulfide Isomerase Activity Protein Binding Peptide Disulfide Oxidoreductase Activity
	Biological Process	Activation Of MAPKKK Activity Apoptotic Process Multicellular Organism Development Cell Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of JNK Cascade Regulation Of Cell Cycle Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of P38MAPK Cascade	Protein Folding Protein Secretion Protein Phosphopantetheinylation Response To Endoplasmic Reticulum Stress Chaperone-mediated Protein Folding
Pathways
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Apolipoprotein A1 levels ( 32203549) Automobile speeding propensity ( 30643258) Brain morphology (MOSTest) ( 32665545) Fibrinogen levels ( 28107422 26561523) General cognitive ability ( 29844566) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Hematocrit ( 32888494) Hemoglobin ( 32888494) Metabolic syndrome ( 31589552) Nonsyndromic cleft lip with cleft palate ( 28232668) Protein quantitative trait loci ( 18464913) Thyroglobulin plasma levels ( 30929638) Triglyceride levels ( 32203549 32154731)	Height ( 20881960)
Interacting Genes		72 interacting genes: ACTN1 AFAP1L1 APP ARPC5L BEND7 BLOC1S2 CCNB1 CDK1 CDKN1A CEP57L1 CFAP44 CNOT9 CRIP2 DCTN2 DDAH2 DDIT4L EEF1A1 EEF1G EIF3G ENKD1 ESR1 EZH2 FAM156A FAM156B GADD45B GADD45GIP1 GDF9 GRAMD4 HAP1 HP IKBKG KAT5 LRIF1 LUC7L LUC7L2 MAP3K4 MED31 MIDN NMB PCNA PDE4DIP PDIA4 PHAX PIAS4 PLEKHM1 PPARA PPARD PPARG PPIL1 PTN PTPRK RAN RARA RASSF10 RBM48 RCN1 RDH13 REL RRP7A RWDD2B RXRA SERPINA4 SGK1 SH3GLB1 SH3GLB2 SMARCB1 TRMT2A TSNAX UTP14A ZNF579 ZNF664 ZNF763	6 interacting genes: APOB BCL2L1 GADD45G KRTAP10-8 KRTAP12-1 LCN2
Entrez ID		10912	9601
HPRD ID		05383	06501
Ensembl ID		ENSG00000130222	ENSG00000155660
Uniprot IDs		O95257	A0A090N8Y2 P13667
PDB IDs		2WAL 3FFM	3IDV
Enriched GO Terms of Interacting Partners?
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