TRAFD1 and KCNMB4

Data Source:
BioGRID (pull down)

		TRAFD1	KCNMB4
Description		TRAF-type zinc finger domain containing 1	potassium calcium-activated channel subfamily M regulatory beta subunit 4
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GO Annotations	Cellular Component		Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Synapse
	Molecular Function	Protein Binding Metal Ion Binding	Protein Binding Calcium-activated Potassium Channel Activity Potassium Channel Regulator Activity
	Biological Process	Negative Regulation Of Innate Immune Response	Action Potential Detection Of Calcium Ion Potassium Ion Transport Chemical Synaptic Transmission Neuronal Action Potential Regulation Of Vasoconstriction Regulation Of Neurotransmitter Secretion Potassium Ion Transmembrane Transport
Pathways			Ca2+ activated K+ channels cGMP effects
Drugs			Procaine Miconazole Trimebutine
Diseases
GWAS		Alanine aminotransferase levels ( 30718733) Alcohol consumption (max-drinks) ( 29460428) Alcohol dependence symptom count ( 29460428) Aspartate aminotransferase levels ( 30718733) Body mass index ( 26426971 25673413) Coffee consumption ( 29367735) Hemoglobin ( 19862010) Hemoglobin levels ( 32327693) Neutrophil count ( 32888494) Platelet count ( 32888494) Plateletcrit ( 32888494) Primary biliary cholangitis ( 26394269) Response to alcohol consumption (flushing response) ( 29460428) Systemic lupus erythematosus ( 28714469) Type 1 diabetes ( 17554300) White blood cell count ( 32888494)	Gut microbiota relative abundance (unassigned genus belonging to family Clostridiales) ( 33208821) Metabolite levels ( 23823483)
Interacting Genes		4 interacting genes: HTT NGLY1 TRAF6 UBC	2 interacting genes: MAL MS4A13
Entrez ID		10906	27345
HPRD ID		10994	05564
Ensembl ID		ENSG00000135148	ENSG00000135643
Uniprot IDs		A0A024RBK4 O14545	Q86W47
PDB IDs		2D9K	5Y7L 6V22 6V35
Enriched GO Terms of Interacting Partners?
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