YIF1A and SNX10

Data Source:
BioGRID (two hybrid)

		YIF1A	SNX10
Description		Yip1 interacting factor homolog A, membrane trafficking protein	sorting nexin 10
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus COPII-coated ER To Golgi Transport Vesicle Integral Component Of Golgi Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Intracellular Membrane-bounded Organelle	Nucleus Endoplasmic Reticulum Centrosome Secretory Granule Extrinsic Component Of Endosome Membrane Apical Cytoplasm
	Molecular Function	Protein Binding	Protein Binding 1-phosphatidylinositol Binding ATPase Binding
	Biological Process	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Transport IRE1-mediated Unfolded Protein Response	Gastric Acid Secretion Intracellular Protein Transport Endocytosis Endosome Organization Osteoclast Differentiation Bone Mineralization Involved In Bone Maturation Tooth Eruption Bone Resorption Calcium Ion Homeostasis Cilium Assembly Protein Localization To Cilium Protein Localization To Centrosome Ruffle Assembly Cellular Response To Leukemia Inhibitory Factor
Pathways		XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Bipolar disorder ( 21926972 31043756) Glucose homeostasis traits ( 25524916)	Dental caries (decayed, missing and filled teeth) ( 31533690) HDL cholesterol ( 30275531) HDL cholesterol levels ( 32203549) Mean reticulocyte volume ( 32888494) Metabolic syndrome ( 31589552) Metabolite levels ( 23823483) Triglyceride levels ( 32203549) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 25673412)
Interacting Genes		72 interacting genes: APOA5 AQP6 BNIP2 C4orf3 CD79A CDK2AP2 CERS2 CNRIP1 CST6 EBP ELOVL4 ERGIC3 FAM210B FARS2 FCER1G FFAR2 GAS7 GJA8 GPR37 GPR42 GPX8 HSD17B11 JOSD2 LNPK LSS MARCHF5 MGST3 MIEF2 MLLT1 MMGT1 MSMO1 MTERF3 MYG1 NDRG4 PLEKHF2 PPIF PTGES PTPN9 RBFA REEP2 REEP4 RIC3 RNF144A SCN3B SCN4B SDCBP SEC23IP SLC10A1 SLC34A1 SLC35C2 SNX10 SNX11 SNX2 SYTL2 SYTL5 TIMMDC1 TMEM139 TMEM14B TMEM17 TMEM225B TMEM248 TMEM31 TMX2 VKORC1 VMA21 WDFY2 YIPF4 YIPF5 ZDHHC16 ZDHHC17 ZFYVE21 ZFYVE27	3 interacting genes: ARL6IP1 RABAC1 YIF1A
Entrez ID		10897	29887
HPRD ID		06755	15409
Ensembl ID		ENSG00000174851	ENSG00000086300
Uniprot IDs		A6NGW1 A8K509 O95070	A0A024RA70 B4DJM0 Q8N5Z3 Q9Y5X0
PDB IDs			4ON3 4PZG
Enriched GO Terms of Interacting Partners?
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