CLPX and CLPP

Data Source:
HPRD (in vitro)

		CLPX	CLPP
Description		caseinolytic mitochondrial matrix peptidase chaperone subunit X	caseinolytic mitochondrial matrix peptidase proteolytic subunit
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Cytosol Endopeptidase Clp Complex Mitochondrial Endopeptidase Clp Complex Mitochondrial Nucleoid	Mitochondrion Mitochondrial Matrix Endopeptidase Clp Complex
	Molecular Function	ATP-dependent Peptidase Activity Protein Binding ATP Binding Zinc Ion Binding Peptidase Activator Activity ATPase Activity Protein Dimerization Activity Unfolded Protein Binding	Endopeptidase Activity ATP-dependent Peptidase Activity Serine-type Endopeptidase Activity Protein Binding Peptidase Activity Identical Protein Binding ATPase Binding
	Biological Process	Protein Folding Proteolysis Positive Regulation Of Peptidase Activity Protein Catabolic Process ATP Metabolic Process Proteolysis Involved In Cellular Protein Catabolic Process	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Membrane Protein Proteolysis Proteolysis Involved In Cellular Protein Catabolic Process
Pathways
Drugs			N-Formylmethionine
Diseases
GWAS
Interacting Genes		2 interacting genes: CLPP FBXL17	16 interacting genes: ABI2 C14orf119 CLPX DTX2 EFEMP1 EFEMP2 GRN KRTAP10-1 NUTF2 P4HA3 PLSCR4 PPP2CA PSMB1 RBPMS TNPO3 TRIM54
Entrez ID		10845	8192
HPRD ID		07478	03074
Ensembl ID		ENSG00000166855	ENSG00000125656
Uniprot IDs		A0A024R5X7 O76031	Q16740
PDB IDs			1TG6 6BBA 6DL7 6H23
Enriched GO Terms of Interacting Partners?
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