ZNF275 and LIN28A

Data Source:
BioGRID (two hybrid)

		ZNF275	LIN28A
Description		zinc finger protein 275	lin-28 homolog A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	P-body Nucleus Nucleolus Cytoplasm Rough Endoplasmic Reticulum Cytosol Polysome Cytoplasmic Stress Granule Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding	G-quadruplex RNA Binding RNA Binding Protein Binding Zinc Ion Binding Translation Initiation Factor Binding MiRNA Binding Polysome Binding Sequence-specific MRNA Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Germ Cell Development MiRNA Catabolic Process Negative Regulation Of Translation Stem Cell Population Maintenance Pre-miRNA Processing RNA 3'-end Processing Positive Regulation Of TOR Signaling Somatic Stem Cell Population Maintenance Positive Regulation Of Neuron Differentiation Negative Regulation Of Glial Cell Differentiation Stem Cell Differentiation Positive Regulation Of Protein Kinase B Signaling RNA 3' Uridylation Cellular Response To Glucose Stimulus Positive Regulation Of Cell Proliferation Involved In Kidney Development Positive Regulation Of Production Of MiRNAs Involved In Gene Silencing By MiRNA Positive Regulation Of Cytoplasmic Translation
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS			Glucose homeostasis traits ( 25524916) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)
Interacting Genes		11 interacting genes: BAHD1 KRTAP10-9 LIN28A RBM10 RNF4 TRAF4 TRIM41 ZNF329 ZNF648 ZNF792 ZNF837	72 interacting genes: MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I ZDHHC17 ZNF275
Entrez ID		10838	79727
HPRD ID		19053	17278
Ensembl ID		ENSG00000063587	ENSG00000131914
Uniprot IDs		A6NFS0	Q9H9Z2
PDB IDs			2CQF 2LI8 5UDZ
Enriched GO Terms of Interacting Partners?
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