SEC24A and TFG

Data Source:
BioGRID (two hybrid)

		SEC24A	TFG
Description		SEC24 homolog A, COPII coat complex component	trafficking from ER to golgi regulator
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Cytosol ER To Golgi Transport Vesicle Membrane COPII Vesicle Coat Endoplasmic Reticulum Exit Site	Golgi Membrane Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Endoplasmic Reticulum Exit Site
	Molecular Function	SNARE Binding Protein Binding Zinc Ion Binding	Protein Binding Identical Protein Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II COPII Vesicle Coating COPII-coated Vesicle Cargo Loading	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling COPII Vesicle Coating
Pathways		Regulation of cholesterol biosynthesis by SREBP (SREBF) COPII-mediated vesicle transport MHC class II antigen presentation Cargo concentration in the ER Antigen Presentation: Folding, assembly and peptide loading of class I MHC	COPII-mediated vesicle transport
Drugs
Diseases			Non-small cell lung cancer Thyroid cancer
GWAS			Refractive error ( 32231278)
Interacting Genes		7 interacting genes: ARID5A CBFA2T3 EWSR1 PEF1 TFG TRIP13 USP54	73 interacting genes: ANXA11 ARHGEF16 ARL15 BOLL BPIFA1 C19orf54 CEP126 CEP55 CRMP1 CRX CSTF2 DAZAP2 DVL3 ERG28 EWSR1 EYA2 FAM168A FOXH1 GBP2 GPRASP1 GRB2 HGS HNRNPF INCA1 INTS11 KHDC1 KRTAP26-1 LASP1 LENG8 MAGED1 MAPK1IP1L MED21 MED25 METTL27 MSS51 MYOT NADSYN1 NID2 OXER1 PEF1 PFDN5 PIN1 PLA2G10 PLEKHG4 PLSCR1 POU2AF1 PPP1R32 PRR20A PRR20B PRR20C PRR20D PRR20E PTPN6 RBPMS RIPPLY2 RNF4 SEC24A SF3A2 SF3B4 SMUG1 SPG21 STAT5B STH TBX19 TEX37 TRIM25 TSSK2 UBAP2 UBE2I VPS37C WWOX ZMYM5 ZNF34
Entrez ID		10802	10342
HPRD ID		08456	03932
Ensembl ID		ENSG00000113615	ENSG00000114354
Uniprot IDs		B4E205 O95486	Q05BK6 Q92734
PDB IDs		2NUP 2NUT 3EGD 3EGX 5VNE 5VNF 5VNG 5VNH 5VNI 5VNJ 5VNK 5VNL 5VNM 5VNN 5VNO
Enriched GO Terms of Interacting Partners?
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