TCFL5 and USF1

Data Source:
BioGRID (pull down)

		TCFL5	USF1
Description		transcription factor like 5	upstream transcription factor 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Male Germ Cell Nucleus Nucleus	Chromatin Nucleus Nucleoplasm Transcription Regulator Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Dimerization Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Enzyme Binding Protein Kinase Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein-containing Complex Binding Protein Heterodimerization Activity Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Multicellular Organism Development Spermatogenesis Cell Differentiation Regulation Of Cell Population Proliferation Regulation Of Cell Differentiation	Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Response To Hypoxia Glucose Metabolic Process Regulation Of Transcription By RNA Polymerase II Response To UV Late Viral Transcription Cellular Response To Insulin Stimulus Glucose Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Carbon Catabolite Regulation Of Transcription Negative Regulation Of Fibrinolysis Lipid Homeostasis
Pathways			Estrogen-dependent gene expression
Drugs
Diseases			Familial combined hyperlipidemia (FCHL)
GWAS		Obesity-related traits ( 23251661)	Granulocyte percentage of myeloid white cells ( 27863252) Inflammatory bowel disease ( 23128233) Metabolite levels (lipoprotein measures) ( 27005778) Night sleep phenotypes ( 27126917)
Interacting Genes		2 interacting genes: TOPBP1 USF1	20 interacting genes: APP ESR1 FBXO7 FOS FOSL1 GTF2I HDAC9 HOMEZ LAP3 MAP3K7CL NFYA PLEKHF2 PPARGC1A PRKDC SNW1 TAOK2 TCF3 TCFL5 TRAF2 USF2
Entrez ID		10732	7391
HPRD ID		05297	01880
Ensembl ID		ENSG00000101190	ENSG00000158773
Uniprot IDs		Q86TP4 Q9UL49	A0A0S2Z4U5 P22415
PDB IDs			1AN4
Enriched GO Terms of Interacting Partners?
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