USP39 and LMAN2L

Data Source:
HPRD (in vitro)

		USP39	LMAN2L
Description		ubiquitin specific peptidase 39	lectin, mannose binding 2 like
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex U4/U6 X U5 Tri-snRNP Complex	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Integral Component Of Membrane COPII-coated ER To Golgi Transport Vesicle
	Molecular Function	Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding	Protein Binding Mannose Binding Metal Ion Binding
	Biological Process	Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome MRNA Processing Cell Cycle RNA Splicing Protein Deubiquitination Protein Phosphopantetheinylation Cell Division	Protein Folding Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Protein Transport
Pathways		mRNA Splicing - Major Pathway	COPII-mediated vesicle transport Cargo concentration in the ER
Drugs
Diseases
GWAS		Neurofibrillary tangles ( 31497858)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Bipolar disorder ( 22182935 21926972 31043756 28072414 20351715) Blood protein levels ( 30072576 29875488)
Interacting Genes		14 interacting genes: ACVR1 APP CHEK2 LRRK2 SAE1 SP1 SRPK1 SRPK2 TRAF6 TRIM25 TRIM26 TRIM39 TRIM5 TRIM8	2 interacting genes: MAL ZDHHC17
Entrez ID		10713	81562
HPRD ID		07165	17286
Ensembl ID		ENSG00000168883	ENSG00000114988
Uniprot IDs		A0A087X1B2 B3KMG1 B3KPG7 B7Z7L9 Q53GS9	B4DI83 B4DVH1 B4E308 Q9H0V9
PDB IDs		3JCR 6AH0 6QW6 6QX9
Enriched GO Terms of Interacting Partners?
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