KLF1 and PRR3

Data Source:
BioGRID (two hybrid)

		KLF1	PRR3
Description		Kruppel like factor 1	proline rich 3
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Metal Ion Binding	RNA Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Erythrocyte Differentiation Positive Regulation Of Transcription, DNA-templated Maternal Process Involved In Female Pregnancy Cellular Response To Peptide
Pathways
Drugs
Diseases		Congenital dyserythropoietic anemias (CDAs)
GWAS		Clozapine-induced agranulocytosis ( 25187353) High light scatter reticulocyte count ( 32888494) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular hemoglobin concentration ( 32888494 27863252) Mean corpuscular volume ( 29403010 32888494 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494 27863252) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252)	Autism spectrum disorder or schizophrenia ( 28540026) Itch intensity from mosquito bite ( 28199695) Neuroticism ( 29255261)
Interacting Genes		32 interacting genes: ARID1A C1QBP CCDC57 CREBBP CSNK2A1 CSNK2A2 DVL3 EFEMP2 EP300 FLI1 GYS1 HDAC1 HNRNPF HNRNPK MKRN3 PATZ1 PCBP1 PRKACA PRR3 RBM10 RBM4B RBPMS2 SMARCA4 SMARCB1 SMARCC1 SMARCC2 SMARCD1 SMARCE1 SNRPC TIAL1 TLE5 VPS37C	21 interacting genes: APOBEC3C ASF1A BCL2L2-PABPN1 CCDC57 CLP1 HNRNPK KHDRBS2 KHDRBS3 KLF1 KRTAP6-2 KRTAP6-3 MYPOP NXF1 PSMA3 RAMAC RBM3 RBMX RBMY1A1 RBMY1F RBMY1J TLE5
Entrez ID		10661	80742
HPRD ID		07197	17915
Ensembl ID		ENSG00000105610	ENSG00000204576
Uniprot IDs		Q13351	B3KQA4 P79522 Q96QB9
PDB IDs		2L2I 2MBH 2N23
Enriched GO Terms of Interacting Partners?
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