CDC42EP3 and COPE

Data Source:
BioGRID (two hybrid)

		CDC42EP3	COPE
Description		CDC42 effector protein 3	COPI coat complex subunit epsilon
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Actin Cytoskeleton	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol COPI Vesicle Coat Transport Vesicle
	Molecular Function	Protein Binding Cytoskeletal Regulatory Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Signal Transduction Rho Protein Signal Transduction Regulation Of Cell Shape Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Transport
Pathways		MAPK6/MAPK4 signaling	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Facial attractiveness (male raters) ( 30946739) Height ( 28552196 20881960 23563607 31562340) Night sleep phenotypes ( 27126917) Rheumatoid arthritis ( 30891314) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Total ventricular volume (Alzheimer's disease interaction) ( 21116278) Youthful appearance (self-reported) ( 32339537)
Interacting Genes		12 interacting genes: CDC42 COPE DAPK1 LRRK1 LRRK2 MFHAS1 RHOQ SEPTIN6 SEPTIN7 SNCA SRPK1 UMPS	14 interacting genes: ARF1 CDC42 CDC42EP3 COPA COPB1 COPB2 COPG1 COPG2 EFHC2 ERCC6 RCHY1 SCYL1 TMED10 WBP2
Entrez ID		10602	11316
HPRD ID		09364	06089
Ensembl ID		ENSG00000163171	ENSG00000105669
Uniprot IDs		Q9UKI2	M0QXB4 O14579
PDB IDs			6TZT 6U3V
Enriched GO Terms of Interacting Partners?
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