SMC2 and ERP44

Data Source:
BioGRID (affinity chromatography technology)

		SMC2	ERP44
Description		structural maintenance of chromosomes 2	endoplasmic reticulum protein 44
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GO Annotations	Cellular Component	Nuclear Chromosome Condensed Chromosome Condensin Complex Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Extracellular Exosome	Extracellular Region Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cell Surface Specific Granule Lumen Extracellular Exosome
	Molecular Function	Chromatin Binding Single-stranded DNA Binding Protein Binding ATP Binding	Protein Disulfide Isomerase Activity Protein Binding
	Biological Process	Mitotic Chromosome Condensation Meiotic Chromosome Condensation Meiotic Chromosome Segregation Cell Division Kinetochore Organization	Protein Folding Response To Unfolded Protein Glycoprotein Metabolic Process Protein Phosphopantetheinylation Response To Endoplasmic Reticulum Stress Neutrophil Degranulation Cell Redox Homeostasis
Pathways		Condensation of Prophase Chromosomes Condensation of Prometaphase Chromosomes Condensation of Prometaphase Chromosomes	Neutrophil degranulation
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Apolipoprotein A1 levels ( 32203549) Basal cell carcinoma ( 31174203) HDL cholesterol levels ( 32203549) Keratinocyte cancer (MTAG) ( 31174203) Oily fish consumption ( 32066663) Orofacial clefts (maternal alcohol consumption interaction) ( 21618603) Pancreatic cancer ( 29422604) Pancreatic ductal adenocarcinoma ( 30541042) Pork consumption ( 32066663) Sensorimotor dexterity ( 31596458)	Preeclampsia ( 23551011)
Interacting Genes		11 interacting genes: ABCC5 CDC42 DISC1 DNMT3B GULP1 LIG4 NCAPD2 PTEN SMC4 SUMO2 TRAF3IP1	3 interacting genes: ERO1A ERO1B ITPR1
Entrez ID		10592	23071
HPRD ID		09277	10290
Ensembl ID		ENSG00000136824	ENSG00000023318
Uniprot IDs		A0A024R158 A8K984 B3KMB1 B7ZLZ7 O95347 Q05BV1 Q05D74 Q6IPS5 Q7Z2X1	A0A384MEE7 Q9BS26
PDB IDs		4U4P	2R2J 5GU6 5GU7 5HQP 5XWM
Enriched GO Terms of Interacting Partners?
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