TXNRD2 and TADA3

Data Source:
BioGRID (two hybrid)

		TXNRD2	TADA3
Description		thioredoxin reductase 2	transcriptional adaptor 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle	SAGA Complex Nucleus Nucleoplasm Ada2/Gcn5/Ada3 Transcription Activator Complex STAGA Complex Transcription Factor TFTC Complex Mitotic Spindle
	Molecular Function	Thioredoxin-disulfide Reductase Activity Protein Binding Flavin Adenine Dinucleotide Binding	Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Nuclear Receptor Binding Protein Domain Specific Binding Nuclear Receptor Coactivator Activity
	Biological Process	Response To Oxygen Radical Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification	Mitotic Cell Cycle Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Protein Deubiquitination Intracellular Estrogen Receptor Signaling Pathway Regulation Of Histone Deacetylation Regulation Of Protein Stability Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Transcription, DNA-templated Regulation Of Tubulin Deacetylation
Pathways		Detoxification of Reactive Oxygen Species	HATs acetylate histones Ub-specific processing proteases
Drugs		Motexafin gadolinium
Diseases
GWAS		Glaucoma ( 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary angle closure) ( 22922875) Glaucoma (primary open-angle) ( 26752265 29891935) Intraocular pressure ( 29785010 31959993 30054594) Lean body mass ( 28552196) Staphylococcus aureus infection ( 24847357)
Interacting Genes		7 interacting genes: BCAS2 GTF2H1 NCOA2 NCOA6 NCOR1 PSMC3 TADA3	32 interacting genes: ADPGK ANKRD12 ANKRD36B AR CCNC EIF3J EP300 ESR1 FAM107B H3-4 HEXIM2 HSPA8 ING5 KDM1A MAGEH1 MFHAS1 NR1I2 PIAS4 RARA RFX1 RXRA RXRB SAP18 SGF29 STX11 TADA2A TP53 TXLNB TXNRD2 USP5 XRCC6 ZNF7
Entrez ID		10587	10474
HPRD ID		18519	04252
Ensembl ID		ENSG00000184470	ENSG00000171148
Uniprot IDs		E7EWK1 Q9NNW7	A0A024R2D7 A8K899 O75528
PDB IDs		1W1E
Enriched GO Terms of Interacting Partners?
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