TXNRD2 and SLC30A9

Data Source:
BioGRID (affinity chromatography technology)

		TXNRD2	SLC30A9
Description		thioredoxin reductase 2	solute carrier family 30 member 9
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle	Nucleus Endoplasmic Reticulum Cytoskeleton Integral Component Of Membrane Cytoplasmic Vesicle
	Molecular Function	Thioredoxin-disulfide Reductase Activity Protein Binding Flavin Adenine Dinucleotide Binding	Chromatin Binding Cation Transmembrane Transporter Activity Nuclear Receptor Binding Nuclear Receptor Coactivator Activity
	Biological Process	Response To Oxygen Radical Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification	Nucleotide-excision Repair Zinc Ion Transport Cellular Zinc Ion Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Cation Transmembrane Transport
Pathways		Detoxification of Reactive Oxygen Species
Drugs		Motexafin gadolinium
Diseases
GWAS		Glaucoma ( 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary angle closure) ( 22922875) Glaucoma (primary open-angle) ( 26752265 29891935) Intraocular pressure ( 29785010 31959993 30054594) Lean body mass ( 28552196) Staphylococcus aureus infection ( 24847357)	anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Helping behaviour (self reported) ( 29324852) Opioid exposure ( 32099098)
Interacting Genes		7 interacting genes: BCAS2 GTF2H1 NCOA2 NCOA6 NCOR1 PSMC3 TADA3	2 interacting genes: ESR1 NCOA2
Entrez ID		10587	10463
HPRD ID		18519	06858
Ensembl ID		ENSG00000184470	ENSG00000014824
Uniprot IDs		E7EWK1 Q9NNW7	A0A0S2Z514 Q6PML9
PDB IDs		1W1E	2ENK
Enriched GO Terms of Interacting Partners?
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