NEBL and XIRP2

Data Source:
BioGRID (two hybrid, pull down, unspecified method)

		NEBL	XIRP2
Description		nebulette	xin actin binding repeat containing 2
Image
GO Annotations	Cellular Component	Stress Fiber Z Disc I Band Extracellular Exosome	Stress Fiber Focal Adhesion
	Molecular Function	Protein Binding Tropomyosin Binding Cytoskeletal Protein Binding Structural Constituent Of Muscle Filamin Binding Actin Filament Binding	Actin Filament Binding
	Biological Process	Muscle Fiber Development Cardiac Muscle Thin Filament Assembly	Heart Development Biological_process Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS		Age-related cognitive decline (global cognition) (slope of z-scores) ( 30954325) Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Atrial fibrillation ( 28416822) Coronary artery aneurysm in Kawasaki disease ( 27171184) Heel bone mineral density ( 30598549) Liver injury in combined anti-retroviral and anti-tuberculosis drug-treated HIV with tuberculosis ( 28388302) Metabolite levels ( 23823483) Ovarian cancer ( 23535730) Photic sneeze reflex ( 27182965) Plasma anti-thyroglobulin and anti-thyroid peroxidase levels (bivariate analysis) ( 29678681) Plasma anti-thyroid peroxidase levels ( 29678681) Pulse pressure ( 27841878) Refractive error ( 32231278) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Sporadic pituitary adenoma ( 26029870) Urate levels in lean individuals ( 25811787) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993) Waist circumference ( 28552196)	Atopic dermatitis ( 25865352) Diabetic peripheral neuropathy in type 2 diabetes ( 31127053) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Plasma renin activity levels ( 29650764)
Interacting Genes		34 interacting genes: ACAP1 ACTB ACTN1 ACTN3 CCDC125 CCDC136 CEP70 FAM9B GMCL1 GOLGA2 GOLGA6A HOMER3 KIFC3 LZTS2 MAD1L1 MIPOL1 MYPN NUTM1 PIBF1 PIK3R3 PRKAB2 QARS1 SPAG5 TRAF1 TRAF2 TRIM27 TRIM55 TRIM63 VCL XIRP1 XIRP2 ZDHHC17 ZGPAT ZYX	5 interacting genes: DYSF FLNC LRRK2 NEB NEBL
Entrez ID		10529	129446
HPRD ID		10403	10267
Ensembl ID		ENSG00000078114	ENSG00000163092
Uniprot IDs		O76041 Q59FZ8	A4UGR9
PDB IDs		4F14	4F14
Enriched GO Terms of Interacting Partners?
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