CAP2 and DTNBP1

Data Source:
BioGRID (affinity chromatography technology)

		CAP2	DTNBP1
Description		cyclase associated actin cytoskeleton regulatory protein 2	dystrobrevin binding protein 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Postsynaptic Density	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Endosome Membrane Postsynaptic Density Microtubule Cytoskeleton Sarcoplasm Axon Growth Cone Midbody Synaptic Vesicle Membrane BLOC-1 Complex Melanosome Membrane Sarcolemma Neuron Projection Dendritic Spine Postsynaptic Membrane Schaffer Collateral - CA1 Synapse Hippocampal Mossy Fiber To CA3 Synapse Glutamatergic Synapse Axon Cytoplasm
	Molecular Function	Actin Binding Protein Binding Adenylate Cyclase Binding Identical Protein Binding	Protein Binding
	Biological Process	Cell Morphogenesis Cytoskeleton Organization Establishment Or Maintenance Of Cell Polarity Signal Transduction Activation Of Adenylate Cyclase Activity CAMP-mediated Signaling Regulation Of Adenylate Cyclase Activity	Positive Regulation Of Neurotransmitter Secretion Negative Regulation Of Protein Kinase Activity Blood Coagulation Anterograde Axonal Transport Positive Regulation Of Gene Expression Regulation Of Dopamine Secretion Neuron Projection Development Actin Cytoskeleton Reorganization Negative Regulation Of Protein Binding Melanosome Organization Regulation Of JUN Kinase Activity Anterograde Synaptic Vesicle Transport Neuron Projection Morphogenesis Dendrite Morphogenesis Platelet Dense Granule Organization Regulation Of Dopamine Receptor Signaling Pathway Negative Regulation Of Protein Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Exocytosis
Pathways		Role of ABL in ROBO-SLIT signaling	Golgi Associated Vesicle Biogenesis
Drugs
Diseases			Hermansky-Pudlak syndrome (HPS)
GWAS		Height ( 18391951) Mitochondrial DNA levels ( 25240745) QT interval ( 29213071) Response to serotonin reuptake inhibitors in major depressive disorder ( 25897834)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Corneal astigmatism ( 30306274) Multiple myeloma ( 27363682) Squamous cell carcinoma ( 31174203)
Interacting Genes		9 interacting genes: ACTG1 ADO ALAS1 CAP1 CFL2 GRXCR1 MT1P3 PRPF40A YWHAE	50 interacting genes: ABI3 AKAP6 ARFIP2 BICRAL BLOC1S5 BLOC1S6 BRF1 CCDC146 CCDC153 CCNA2 CCND3 CMYA5 DCTN1 DGCR6L DST DTNA DTNB ELOVL7 HAUS1 IFT20 IPO5 KALRN KANSL1 KIAA0408 KIFC3 KRT75 MACF1 NBEA NDN NECAB2 NUF2 OIP5 P4HA3 PSME3 RAB11A RBSN SDCBP SFR1 SHFL SNAPIN SRGAP3 SSC5D SYNE1 TRAF3IP1 TRIM2 TRIM27 TRIM9 VRK2 WASHC3 ZNF490
Entrez ID		10486	84062
HPRD ID		10808	06190
Ensembl ID		ENSG00000112186	ENSG00000047579
Uniprot IDs		P40123 Q5JPJ8	A0A087WYP9 A0A0S2Z5U8 A6NFV8 D6RJC6 Q96EV8
PDB IDs
Enriched GO Terms of Interacting Partners?
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