SLC30A9 and TXNRD2

Data Source:
BioGRID (affinity chromatography technology)

		SLC30A9	TXNRD2
Description		solute carrier family 30 member 9	thioredoxin reductase 2
Image
GO Annotations	Cellular Component	Nucleus Endoplasmic Reticulum Cytoskeleton Integral Component Of Membrane Cytoplasmic Vesicle	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Intracellular Membrane-bounded Organelle
	Molecular Function	Chromatin Binding Cation Transmembrane Transporter Activity Nuclear Receptor Binding Nuclear Receptor Coactivator Activity	Thioredoxin-disulfide Reductase Activity Protein Binding Flavin Adenine Dinucleotide Binding
	Biological Process	Nucleotide-excision Repair Zinc Ion Transport Cellular Zinc Ion Homeostasis Positive Regulation Of Transcription By RNA Polymerase II Cation Transmembrane Transport	Response To Oxygen Radical Cellular Response To Oxidative Stress Cell Redox Homeostasis Cellular Oxidant Detoxification
Pathways			Detoxification of Reactive Oxygen Species
Drugs			Motexafin gadolinium
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Helping behaviour (self reported) ( 29324852) Opioid exposure ( 32099098)	Glaucoma ( 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary angle closure) ( 22922875) Glaucoma (primary open-angle) ( 26752265 29891935) Intraocular pressure ( 29785010 31959993 30054594) Lean body mass ( 28552196) Staphylococcus aureus infection ( 24847357)
Interacting Genes		2 interacting genes: ESR1 NCOA2	7 interacting genes: BCAS2 GTF2H1 NCOA2 NCOA6 NCOR1 PSMC3 TADA3
Entrez ID		10463	10587
HPRD ID		06858	18519
Ensembl ID		ENSG00000014824	ENSG00000184470
Uniprot IDs		A0A0S2Z514 Q6PML9	E7EWK1 Q9NNW7
PDB IDs		2ENK	1W1E
Enriched GO Terms of Interacting Partners?
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