TUBGCP3 and PCNT

Data Source:
HPRD (in vivo)

		TUBGCP3	PCNT
Description		tubulin gamma complex associated protein 3	pericentrin
Image			No pdb structure
GO Annotations	Cellular Component	Equatorial Microtubule Organizing Center Gamma-tubulin Complex Cytoplasm Centrosome Centriole Spindle Polar Microtubule Cytosol Gamma-tubulin Small Complex Membrane	Centrosome Centriole Cytosol Microtubule Membrane Centriolar Satellite
	Molecular Function	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding	Protein Binding Calmodulin Binding Molecular Adaptor Activity
	Biological Process	Mitotic Cell Cycle Microtubule Nucleation Single Fertilization Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle	G2/M Transition Of Mitotic Cell Cycle Microtubule Cytoskeleton Organization Mitotic Spindle Organization Signal Transduction Regulation Of G2/M Transition Of Mitotic Cell Cycle Cilium Assembly Positive Regulation Of Intracellular Protein Transport Ciliary Basal Body-plasma Membrane Docking
Pathways		Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes	Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs
Diseases			Microcephalic osteodysplastic primordial dwarfism, type II (MOPD II) Seckel syndrome
GWAS		Glycated hemoglobin levels ( 20858683)	Heel bone mineral density ( 30598549) Pre-treatment viral load in HIV-1 infection ( 31219150) Treatment resistant depression ( 30468137)
Interacting Genes		6 interacting genes: AKAP9 DNAJB6 IMMT PCNT TUBG1 TUBG2	11 interacting genes: AKAP9 CALM1 CALM2 CCP110 CEP55 DISC1 PCM1 TP53BP1 TUBG1 TUBGCP2 TUBGCP3
Entrez ID		10426	5116
HPRD ID		10289	05804
Ensembl ID		ENSG00000126216	ENSG00000160299
Uniprot IDs		A0A087WU06 B4DYP7 Q96CW5	O95613
PDB IDs		6V6B 6V6S 6X0U
Enriched GO Terms of Interacting Partners?
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