KLHL41 and NRAP

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid, in vitro)

		KLHL41	NRAP
Description		kelch like family member 41	nebulin related anchoring protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Nucleoplasm Cytoplasm Endoplasmic Reticulum Membrane Cytosol Cytoskeleton Plasma Membrane Pseudopodium M Band Cul3-RING Ubiquitin Ligase Complex Sarcoplasmic Reticulum Membrane	Fascia Adherens Muscle Tendon Junction Z Disc
	Molecular Function	Protein Binding	Actin Binding Protein Binding Metal Ion Binding Actin Filament Binding Muscle Alpha-actinin Binding
	Biological Process	Striated Muscle Contraction Protein Ubiquitination Myofibril Assembly Regulation Of Lateral Pseudopodium Assembly Skeletal Muscle Cell Differentiation Post-translational Protein Modification Sarcomere Organization Regulation Of Myoblast Differentiation Skeletal Muscle Fiber Development Regulation Of Myoblast Proliferation Regulation Of Skeletal Muscle Cell Differentiation	Biological_process Muscle Fiber Development Cardiac Muscle Thin Filament Assembly
Pathways		Neddylation Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) Plasma factor VII activating protease levels ( 30070759) QT interval ( 29874175)
Interacting Genes		9 interacting genes: C4orf45 IFRD1 MYBPC1 NRAP POMP RBM4 RCHY1 SLC2A4 TCAP	8 interacting genes: ACTA1 ACTB ACTN3 KLHL41 PRKAA2 TLN1 TRIM63 VCL
Entrez ID		10324	4892
HPRD ID		07610	04189
Ensembl ID		ENSG00000239474	ENSG00000197893
Uniprot IDs		O60662	A0A0A0MRM2 Q86VF7
PDB IDs
Enriched GO Terms of Interacting Partners?
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