SIGMAR1 and SPINK4

Data Source:
BioGRID (biochemical)

		SIGMAR1	SPINK4
Description		sigma non-opioid intracellular receptor 1	serine peptidase inhibitor Kazal type 4
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane	Extracellular Region
	Molecular Function	Opioid Receptor Activity Protein Binding	Serine-type Endopeptidase Inhibitor Activity Protein Binding
	Biological Process	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization	Negative Regulation Of Endopeptidase Activity
Pathways		Potential therapeutics for SARS
Drugs		Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS			Influenza A (H1N1) infection ( 26379185) Mild influenza (H1N1) infection ( 26379185) Severe influenza A (H1N1) infection ( 26379185)
Interacting Genes		3 interacting genes: ANK2 ITPR3 PDZD11	1 interacting genes: SGTB
Entrez ID		10280	27290
HPRD ID		03580	11598
Ensembl ID		ENSG00000147955	ENSG00000122711
Uniprot IDs		A2A3U5 B4DR71 Q99720	O60575 V9HWG8
PDB IDs		5HK1 5HK2 6DJZ 6DK0 6DK1
Enriched GO Terms of Interacting Partners?
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