SIGMAR1 and PHF24

Data Source:
BioGRID (affinity chromatography technology)

		SIGMAR1	PHF24
Description		sigma non-opioid intracellular receptor 1	PHD finger protein 24
Image
GO Annotations	Cellular Component	Nuclear Envelope Nuclear Inner Membrane Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Postsynaptic Density Membrane Integral Component Of Membrane Growth Cone Cytoplasmic Vesicle Postsynaptic Density Membrane
	Molecular Function	Opioid Receptor Activity Protein Binding	Protein Binding Metal Ion Binding
	Biological Process	Lipid Transport Nervous System Development Cell Death In Response To Hydrogen Peroxide Opioid Receptor Signaling Pathway Regulation Of Neuron Apoptotic Process Protein Homotrimerization	Gamma-aminobutyric Acid Signaling Pathway Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Synaptic Transmission, GABAergic Detection Of Mechanical Stimulus Involved In Sensory Perception Of Pain
Pathways		Potential therapeutics for SARS
Drugs		Amitriptyline Remoxipride Haloperidol Dextromethorphan Nortriptyline Fenfluramine Pentazocine Cocaine Hydrocodone Sertraline Dimethyltryptamine Prasterone Phencyclidine Noscapine Captodiame Pentoxyverine
Diseases
GWAS
Interacting Genes		3 interacting genes: ANK2 ITPR3 PDZD11	5 interacting genes: GNAI3 PFDN5 THBD TRIM35 ZNF552
Entrez ID		10280	23349
HPRD ID		03580	19412
Ensembl ID		ENSG00000147955	ENSG00000122733
Uniprot IDs		A2A3U5 B4DR71 Q99720	Q9UPV7
PDB IDs		5HK1 5HK2 6DJZ 6DK0 6DK1	1WIL 5XHT
Enriched GO Terms of Interacting Partners?
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