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CDK2AP2 and EED
Data Source:
BioGRID
(two hybrid)
CDK2AP2
EED
Description
cyclin dependent kinase 2 associated protein 2
embryonic ectoderm development
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Microtubule
Nucleus
Nucleoplasm
Chromosome
Cytosol
ESC/E(Z) Complex
Molecular Function
Protein Binding
RNA Polymerase II Transcription Corepressor Binding
Protein Binding
Nucleosome Binding
Histone Methyltransferase Activity
Identical Protein Binding
Histone Methyltransferase Activity (H3-K27 Specific)
Biological Process
Regulation Of Microtubule Cytoskeleton Organization
Regulation Of Stem Cell Division
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Chromatin Silencing
Viral Process
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of G0 To G1 Transition
Histone H3-K27 Methylation
Pathways
PRC2 methylates histones and DNA
Oxidative Stress Induced Senescence
PKMTs methylate histone lysines
Activation of anterior HOX genes in hindbrain development during early embryogenesis
Regulation of PTEN gene transcription
Regulation of PTEN gene transcription
Transcriptional Regulation by E2F6
HCMV Early Events
Drugs
Diseases
GWAS
Refractive error (
32231278
)
Smoking initiation (ever regular vs never regular) (
30679032
)
Smoking status (ever vs never smokers) (
30643258
)
Interacting Genes
17 interacting genes:
A2M
APP
CDK2AP1
DBN1
EED
EEF1G
HSF4
IKZF1
MBTPS1
MRFAP1L1
PYCR1
RCC1
RPLP1
TRA2A
WARS1
YIF1A
ZBTB48
42 interacting genes:
AEBP2
ANXA5
AR
BRCA1
CDK2AP2
CTSL
DNMT1
DNMT3A
DNMT3B
DUSP23
EHMT1
EPC2
EZH1
EZH2
FHL1
H1-1
H3C1
HDAC1
HDAC2
HDAC3
ITGA4
ITGAE
ITGB7
MAP1LC3B
NUDT21
PJA1
PPP1CA
PPP1R8
PRDM14
RACK1
RPS10
SELENBP1
SMYD3
SRPK2
TGS1
TRIM55
TRIM63
TSC22D1
UBE2W
YY1
ZBED8
ZFP42
Entrez ID
10263
8726
HPRD ID
13242
09343
Ensembl ID
ENSG00000167797
ENSG00000074266
Uniprot IDs
O75956
Q6IAV4
E9PJK2
O75530
PDB IDs
2M1L
3IIW
3IIY
3IJ0
3IJ1
3IJC
3JPX
3JZG
3JZH
3JZN
3K26
3K27
4W2R
4X3E
5GSA
5H13
5H14
5H15
5H17
5H19
5H24
5H25
5HYN
5IJ7
5IJ8
5K0M
5LS6
5TTW
5U5H
5U5K
5U5T
5U62
5U69
5U6D
5U8A
5U8F
5WG6
5WP3
5WUK
6B3W
6C23
6C24
6SFB
6SFC
6U4Y
6W7F
6W7G
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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