CALCOCO2 and SNRPB

Data Source:
BioGRID (two hybrid)

		CALCOCO2	SNRPB
Description		calcium binding and coiled-coil domain 2	small nuclear ribonucleoprotein polypeptides B and B1
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GO Annotations	Cellular Component	Autophagosome Membrane Nucleus Cytoplasm Autophagosome Cytosol Cytoskeleton Membrane PML Body Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP U7 SnRNP U1 SnRNP U2 SnRNP U4 SnRNP U12-type Spliceosomal Complex Telomerase Holoenzyme Complex Cytoplasm Cytosol Small Nuclear Ribonucleoprotein Complex Methylosome SMN-Sm Protein Complex U4/U6 X U5 Tri-snRNP Complex U2-type Prespliceosome U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Histone Pre-mRNA 3'end Processing Complex
	Molecular Function	Protein Binding Protein Homodimerization Activity Metal Ion Binding	RNA Binding Protein Binding Telomerase RNA Binding Histone Pre-mRNA DCP Binding U1 SnRNP Binding U2 SnRNP Binding
	Biological Process	Viral Process Response To Interferon-gamma Xenophagy Positive Regulation Of Autophagosome Maturation	Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription Protein Methylation Brain Development Histone MRNA Metabolic Process RNA Splicing Import Into Nucleus
Pathways			SLBP independent Processing of Histone Pre-mRNAs snRNP Assembly mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway RNA Polymerase II Transcription Termination SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Chronotype ( 30696823) Type 2 diabetes ( 29358691 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382)
Interacting Genes		180 interacting genes: ABLIM1 ADSL AKAP17A AMMECR1 AP5B1 APEX2 ARHGEF39 ARHGEF5 ARNT2 ATG5 AXIN1 BAHD1 BCL6B BEX2 CBX8 CCDC120 CCDC185 CCDC33 CCNH CDC7 CELA2B CEP57L1 CHCHD3 CNNM3 CPNE7 CWF19L2 DAXX DAZAP2 DBNDD2 DCTN4 DCX DDIT4L DDX6 DOCK2 DUSP12 DUSP26 EEF1E1 EFHC1 ELOA2 ENKD1 EXOSC5 FAM107A FAM161A FAM168A FAM189A2 FAM214B FAM90A1 FARS2 FASTK FBF1 FBXL18 FKBPL FNDC11 FOXD4L3 FXR2 GABARAPL1 GABARAPL2 GATAD2B GCA GEMIN4 GIT2 GLYCTK HDAC4 HDAC7 HLX HNRNPLL HOXB5 HOXB9 IKBKG IL16 IQUB KANSL1 KAT7 KLHL35 KLHL42 LENG1 LGALS8 LIMS2 LITAF LMF2 LMO2 LMO4 LNX1 LONRF1 LSM4 MAGOHB MAP1LC3C MCM10 METTL17 MID2 MOS MTPAP MVP MXI1 MYH6 MYO6 NAA10 NDN NFU1 ORC5 PCGF1 PEF1 PEG10 PFDN5 PHF1 PIAS4 PLEKHN1 POLI POLR2A PPP1R18 PRKAA2 PRKAB2 PRPF18 PRPF31 PSMA1 PSME4 PTBP1 PTBP2 QARS1 RAB35 RABL6 RBM15 RHPN1 RIN1 RNF11 RPA2 RPL9 RPS27A RTN4IP1 RTP5 RXRB SCAND1 SCNM1 SDCBP SETD5 SHC1 SLC15A3 SMARCD1 SMCP SNRPB SPATA24 SRI STAMBPL1 STK16 TACO1 TBC1D22B TBK1 TBKBP1 TBRG4 TCL1A TEKT3 TENT2 TLE5 TP53RK TRAF2 TRAF4 TRAF6 TSGA10IP TTC23L UBAC2 USP2 VARS1 VPS72 ZBTB4 ZC2HC1C ZNF101 ZNF205 ZNF337 ZNF408 ZNF414 ZNF426 ZNF451 ZNF564 ZNF581 ZNF638 ZNF648 ZNF688 ZNF696 ZNF774 ZNF80	89 interacting genes: AKAP9 ASCC2 BAG4 BANP C10orf55 CALCOCO2 CD2BP2 CDKN2A CEP55 CLNS1A COA7 COG6 COIL CREM CTDP1 CYSRT1 DAB1 DDX20 DHX9 ERG28 EXOSC8 FAM168B FHL3 FNBP4 FUBP1 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GIGYF1 GIGYF2 GOLGA2 HNRNPH1 HOXA1 IL7R INCA1 KRT34 KRT40 KRTAP19-1 KRTAP19-6 KRTAP6-1 KRTAP6-2 KRTAP6-3 L3MBTL3 LSM11 LSM8 MAGI2 MBD3L1 OIP5 OOEP PFDN5 PLEKHB2 PNMA1 PRMT5 PRMT7 PRR20A PRR20B PRR20C PRR20D PRR20E PRR22 PSMA3 RBPMS RFX6 SERTAD3 SKIV2L SMN1 SMN2 SMNDC1 SNRPD1 SNRPD3 SNUPN SP3 SPAG8 SS18L1 STRAP STXBP2 STXBP3 TFIP11 TOP3B TRAF4 TRIM23 UBQLN2 UBXN11 USP54 WBP4 WDR77 WWP2 ZNF143
Entrez ID		10241	6628
HPRD ID		06846	01655
Ensembl ID		ENSG00000136436	ENSG00000125835
Uniprot IDs		Q13137	P14678 Q66K91
PDB IDs		2MXP 3VVV 3VVW 4GXL 4HAN 4XKL 5AAQ 5Z7A 5Z7L	1D3B 3CW1 3JCR 3PGW 4PJO 4WZJ 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9 6V4X 6Y53 6Y5Q 7A5P
Enriched GO Terms of Interacting Partners?
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