DNAL4 and DDX17

Data Source:
BioGRID (affinity chromatography technology)

		DNAL4	DDX17
Description		dynein axonemal light chain 4	DEAD-box helicase 17
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Plasma Membrane Cilium Dynein Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Speck Ribonucleoprotein Complex
	Molecular Function	Microtubule Motor Activity Protein Binding Identical Protein Binding Dynein Intermediate Chain Binding Dynein Light Intermediate Chain Binding	Transcription Coactivator Activity RNA Binding RNA Helicase Activity Protein Binding ATP Binding RNA-dependent ATPase Activity
	Biological Process	Microtubule-based Movement Positive Regulation Of ATP-dependent Microtubule Motor Activity, Plus-end-directed	Alternative MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Epithelial To Mesenchymal Transition Regulation Of Transcription By RNA Polymerase II RRNA Processing RNA Processing MiRNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Androgen Receptor Signaling Pathway Gene Silencing By RNA Myoblast Differentiation Positive Regulation Of Transcription By RNA Polymerase II Defense Response To Virus Regulation Of Skeletal Muscle Cell Differentiation
Pathways		Retrograde neurotrophin signalling	SUMOylation of transcription cofactors
Drugs
Diseases
GWAS			Menopause (age at onset) ( 26414677) Resting heart rate ( 27798624) Sleep duration ( 30846698)
Interacting Genes		16 interacting genes: CAMK2D CHIC2 DYNLL1 DYNLL2 FHL5 GNA14 GPBP1 KRTAP10-3 KRTAP12-3 KRTAP9-8 NFATC2IP NOTCH2NLA NTAQ1 NUDT22 SCTR TRIM54	38 interacting genes: APBB1 APP BYSL CCDC187 CREBBP CSNK2A1 DDX5 DDX6 ESR1 FBL FXR2 GAS8 GRB2 HDAC1 HNRNPH1 HNRNPH3 HNRNPK LNX1 NCOA1 NCOA2 NCOA3 PIN1 PTK6 PTPRD RBM10 RBM14 RBM15 RBM4 RBM5 SF1 SF3B4 SNRNP70 SORBS3 SREK1 SUMO2 WBP11 WBP2 YWHAG
Entrez ID		10126	10521
HPRD ID		13239	10532
Ensembl ID		ENSG00000100246	ENSG00000100201
Uniprot IDs		O96015	Q59F66 Q92841
PDB IDs			6UV0 6UV1 6UV2 6UV3 6UV4
Enriched GO Terms of Interacting Partners?
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