CDH12 and CDH18

Data Source:
HPRD (in vivo, in vitro)

		CDH12	CDH18
Description		cadherin 12	cadherin 18
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Adherens Junction Integral Component Of Membrane Catenin Complex	Plasma Membrane Adherens Junction Integral Component Of Membrane Catenin Complex
	Molecular Function	Calcium Ion Binding Cadherin Binding	Calcium Ion Binding Cadherin Binding
	Biological Process	Cell Morphogenesis Cell-cell Junction Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Multicellular Organism Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules	Cell Morphogenesis Cell-cell Junction Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Multicellular Organism Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways		Adherens junctions interactions	Adherens junctions interactions
Drugs
Diseases
GWAS		Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (physical activity interaction) ( 28448500) Brooding (response to stress) ( 30886212) Dimensional psychopathology (Cognitive) ( 29496196) Low white blood cell count (conditioned on rs2814778) ( 29596498) Mosquito bite size ( 28199695) Smoking initiation ( 30617275) Smoking initiation (ever regular vs never regular) ( 30679032) Waist circumference ( 19557197)	Childhood body mass index ( 33045005) Depression (quantitative trait) ( 20800221) Diabetes (gestational) ( 31269844) Erectile dysfunction ( 30583798) Metabolic coherence (transcriptomic) ( 30852652) Mitochondrial DNA levels ( 25240745) Obesity in adult survivors of childhood cancer exposed to cranial radiation ( 25963547) Obstetric antiphospholipid syndrome ( 28424481) Resistant hypertension ( 31545351) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603) Serum metabolite concentrations in chronic kidney disease ( 29545352) Type 2 diabetes ( 31049640)
Interacting Genes		2 interacting genes: CDH18 CDH7	4 interacting genes: CDH12 CDH6 CDH9 MYOG
Entrez ID		1010	1016
HPRD ID		11081	04314
Ensembl ID		ENSG00000154162	ENSG00000145526
Uniprot IDs		P55289	D6RER2 Q13634
PDB IDs
Enriched GO Terms of Interacting Partners?
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