USH1C and CDH23

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo, two hybrid)

		USH1C	CDH23
Description		USH1 protein network component harmonin	cadherin related 23
Image
GO Annotations	Cellular Component	Photoreceptor Outer Segment Photoreceptor Inner Segment Stereocilia Ankle Link Complex Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microvillus Brush Border Photoreceptor Connecting Cilium Stereocilium Stereocilium Tip Apical Part Of Cell Synapse	Membrane Integral Component Of Membrane Catenin Complex Stereocilium
	Molecular Function	Protein Binding Spectrin Binding Actin Filament Binding	Calcium Ion Binding Protein Binding Cadherin Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Sensory Perception Of Sound Parallel Actin Filament Bundle Assembly Regulation Of Microvillus Length Cellular Protein-containing Complex Assembly Inner Ear Morphogenesis Inner Ear Auditory Receptor Cell Differentiation Photoreceptor Cell Maintenance Retinal Cone Cell Development Sensory Perception Of Light Stimulus Equilibrioception Actin Filament Bundle Assembly Inner Ear Receptor Cell Stereocilium Organization Protein Localization To Microvillus Brush Border Assembly	Calcium Ion Transport Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Visual Perception Sensory Perception Of Sound Locomotory Behavior Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Photoreceptor Cell Maintenance Response To Stimulus Sensory Perception Of Light Stimulus Equilibrioception Regulation Of Cytosolic Calcium Ion Concentration Inner Ear Receptor Cell Stereocilium Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways
Drugs
Diseases		Usher syndrome (US) Deafness, autosomal recessive	Usher syndrome (US) Deafness, autosomal recessive
GWAS		Body mass index ( 26426971) Macular thickness ( 30535121) Night sleep phenotypes ( 27126917)	Age at smoking initiation in chronic obstructive pulmonary disease ( 21685187) Bipolar disorder (body mass index interaction) ( 24322204) Blood protein levels ( 29875488) Cerebrospinal fluid beta-site APP cleaving enzyme levels ( 29751835) Cognitive performance (processing speed) ( 31598132) Decline in glucose metabolism in posterior cingulate cortex ( 29130521) Diffusing capacity of the lung for carbon monoxide traits ( 30049742) Diisocyanate-induced asthma ( 25918132) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Kidney function decline traits ( 25493955) Monocyte count ( 27863252) Monocyte percentage of white cells ( 32888494) Progranulin levels ( 29186428) Selective IgA deficiency ( 27723758) Self-reported risk-taking behaviour ( 30271922) Systemic lupus erythematosus ( 33536424) Vitiligo ( 22951725)
Interacting Genes		13 interacting genes: ANKS4B CDH23 CTNNAL1 ENKD1 FBXO7 MIPOL1 MYO7A PCDHB12 PRKAA2 QKI RAC1 USH1G USHBP1	3 interacting genes: CLK1 MYO7A USH1C
Entrez ID		10083	64072
HPRD ID		09241	05699
Ensembl ID		ENSG00000006611	ENSG00000107736
Uniprot IDs		A0A0S2Z4U9 A0A0S2Z4V1 Q9Y6N9	A0A087WYR8 A5D6V9 Q6P152 Q8N5B3 Q9H251
PDB IDs		1X5N 2KBQ 2KBR 2KBS 2LSR 3K1R 5F3X 5MV8 5MV9 5XBF	2KBR 2KBS 2LSR 5TFM 5VVM 5WJ8
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?