SCAMP2 and ST3GAL3

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SCAMP2	ST3GAL3
Description		secretory carrier membrane protein 2	ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Apparatus Integral Component Of Membrane Transport Vesicle Trans-Golgi Network Membrane Intracellular Membrane-bounded Organelle Recycling Endosome Membrane Extracellular Exosome	Golgi Membrane Extracellular Region Integral Component Of Membrane Golgi Cisterna Membrane
	Molecular Function	Protein Binding	Protein Binding N-acetyllactosaminide Alpha-2,3-sialyltransferase Activity Sialyltransferase Activity
	Biological Process	Post-Golgi Vesicle-mediated Transport Protein Transport	Protein Glycosylation O-glycan Processing Keratan Sulfate Biosynthetic Process Sialylation
Pathways			Pre-NOTCH Processing in Golgi Keratan sulfate biosynthesis Defective ST3GAL3 causes MCT12 and EIEE15 Sialic acid metabolism Lewis blood group biosynthesis Maturation of protein 3a Maturation of spike protein Maturation of protein 3a Termination of O-glycan biosynthesis
Drugs
Diseases			Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS		Caffeine consumption ( 21490707) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 32888494 27863252) Multiple sclerosis ( 31604244) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)	Aging (time to event) ( 21782286) Amyotrophic lateral sclerosis (age of onset) ( 22959728) Attention deficit hyperactivity disorder ( 29325848) Autism spectrum disorder or schizophrenia ( 28540026) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) General cognitive ability ( 29844566) Household income ( 31844048) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Left-handedness ( 32989287) Monocyte percentage of white cells ( 32888494) Non-lobar intracerebral hemorrhage (MTAG) ( 31430377) Refractive error ( 32231278) Schizophrenia ( 28991256)
Interacting Genes		5 interacting genes: ARIH2 SCAMP1 SLC9A7 SNAP23 ST3GAL3	5 interacting genes: ACTG1 RPL8 SCAMP2 TTR ZBTB5
Entrez ID		10066	6487
HPRD ID		06073	05930
Ensembl ID		ENSG00000140497	ENSG00000126091
Uniprot IDs		A0A140VK92 A8K769 O15127	A0A2R8Y732 Q11203
PDB IDs
Enriched GO Terms of Interacting Partners?
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