ABCC9 and EEF1G

Data Source:
HPRD (two hybrid)

		ABCC9	EEF1G
Description		ATP binding cassette subfamily C member 9	eukaryotic translation elongation factor 1 gamma
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Inward Rectifying Potassium Channel Membrane Sarcomere Potassium Ion-transporting ATPase Complex	Nucleus Cytoplasm Endoplasmic Reticulum Cytosol Membrane Extracellular Exosome
	Molecular Function	Cation Channel Activity Potassium Channel Activity ATP Binding Sulfonylurea Receptor Activity ATP-activated Inward Rectifier Potassium Channel Activity Potassium Channel Regulator Activity ATPase Activity ATPase-coupled Cation Transmembrane Transporter Activity Transmembrane Transporter Activity ATPase-coupled Transmembrane Transporter Activity Ion Channel Binding	Translation Elongation Factor Activity Protein Binding Cadherin Binding
	Biological Process	Response To ATP Defense Response To Virus Transmembrane Transport Cardiac Conduction Potassium Ion Transmembrane Transport Cation Transmembrane Transport Inorganic Cation Transmembrane Transport Transport Across Blood-brain Barrier Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane	Translational Elongation Glutathione Metabolic Process Response To Virus
Pathways		ATP sensitive Potassium channels ABC-family proteins mediated transport Ion homeostasis Defective ABCC9 causes CMD10, ATFB12 and Cantu syndrome	Eukaryotic Translation Elongation
Drugs		ATP Glyburide Nicorandil
Diseases		Atrial fibrillation
GWAS		Appendicular lean mass ( 33097823) Birth weight ( 27680694) Gout ( 22179738) Hippocampal sclerosis of aging ( 24770881) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Obesity-related traits ( 23251661) Offspring birth weight ( 31043758) Pulse pressure ( 30224653 30578418)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Waist-to-hip ratio adjusted for body mass index ( 28448500)
Interacting Genes		6 interacting genes: EEF1G HSPB2 KCNJ11 KCNJ8 LDHA STX1A	93 interacting genes: ABCC9 ADAP2 AKT1 ANKRD28 ARF1 ARIH2 C11orf58 C1orf174 CARS1 CBX8 CCDC106 CCT7 CDC42 CDK2AP2 CDK5RAP2 CHFR CRELD1 CSTF2 CXCL13 DKC1 DLEU1 DRD3 DYSF ECH1 EEF1B2 EEF1D EEF1DP3 EFNA1 EID2B ENOX1 FEN1 FOXG1 GADD45A GADD45G GET4 GSK3B GSTO1 HARS1 HDAC5 HLTF HMOX2 HNRNPH3 ILF2 KARS1 KLHL18 LARS1 LINC01554 LZTS1 MCRIP2 MED31 MLH1 MTNR1A MVD NADK NCK2 NDRG1 NUDT21 NUDT3 NUP85 OGFOD2 PDCD5 PHACTR3 PLEKHA4 PLGRKT PSMD11 PTK2 PTPN4 PTPRF PTPRS RBM6 RECQL5 RGL2 RPL4P5 RPS28 SAT1 SFRP2 SKIL SLC22A2 SNAPIN SNRPD2 SUMO2 TNNT1 TP53I3 TRIB3 TRIM55 TRIM63 TUBB3 UCHL5 WDR33 YWHAG ZBED8 ZDHHC17 ZNF24
Entrez ID		10060	1937
HPRD ID		03258	11745
Ensembl ID		ENSG00000069431	ENSG00000254772
Uniprot IDs		A0A024RAV7 O60706	P26641 Q53YD7
PDB IDs			1PBU 5DQS 5JPO
Enriched GO Terms of Interacting Partners?
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