MICOS10-NBL1 and LRIG1

Data Source:
BioGRID (two hybrid)

		MICOS10-NBL1	LRIG1
Description		MICOS10-NBL1 readthrough	leucine rich repeats and immunoglobulin like domains 1
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GO Annotations	Cellular Component		Extracellular Space Plasma Membrane Integral Component Of Membrane Extracellular Matrix
	Molecular Function		Protein Binding
	Biological Process		Sensory Perception Of Sound Hair Cycle Process Otolith Morphogenesis Innervation
Pathways			Signaling by EGFR Negative regulation of MET activity
Drugs
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs) ( 23648065) Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin) ( 23648065) Antibody status in Tripanosoma cruzi seropositivity ( 24324551) Atrial fibrillation ( 30061737 29892015) Birth weight ( 31043758) Blood urea nitrogen levels ( 29403010) Carotid intima media thickness ( 21909108) Chronic kidney disease ( 29124443) Colorectal cancer ( 26151821) Colorectal cancer or advanced adenoma ( 30510241) Creatinine levels ( 29124443) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Estimated glomerular filtration rate ( 29124443) Hyperuricemia ( 29124443) Intraocular pressure ( 30054594) Mean corpuscular hemoglobin ( 32888494 27863252) Mean corpuscular volume ( 32888494 27863252) Non-glioblastoma glioma ( 28346443) Orofacial clefts ( 33137956) Pulse pressure ( 27841878) QRS duration ( 27577874 21076409 27659466) Red cell distribution width ( 32888494) Refractive error ( 32231278) Renal function-related traits (BUN) ( 22797727) Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 3 peripheral neuropathy) ( 24554482) Retinal detachment or retinal break ( 31816047) Serum uric acid levels ( 29124443) Systolic blood pressure ( 27841878) Type 2 diabetes ( 25760438) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		11 interacting genes: DPEP2NB HPCAL1 KRTAP11-1 LRIG1 MEOX2 MRPL12 NCALD PLA2G2F SLPI UBQLN1 UBQLN2	5 interacting genes: CBL GLRX3 MICOS10-NBL1 NBL1 ZBTB16
Entrez ID		100532736	26018
HPRD ID			10057
Ensembl ID		ENSG00000158747	ENSG00000144749
Uniprot IDs		P41271	Q96JA1
PDB IDs		4X1J 4YU8	4U7L 4U7M
Enriched GO Terms of Interacting Partners?
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