BCL2L2-PABPN1 and BMF

Data Source:
BioGRID (two hybrid)

		BCL2L2-PABPN1	BMF
Description		BCL2L2-PABPN1 readthrough	Bcl2 modifying factor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Acrosomal Vesicle Mitochondrial Outer Membrane Cytosol Plasma Membrane Myosin Complex
	Molecular Function		Protein Binding
	Biological Process		Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Negative Regulation Of Autophagy Positive Regulation Of Protein-containing Complex Assembly Cellular Response To UV Positive Regulation Of Apoptotic Process Anoikis Positive Regulation Of Release Of Cytochrome C From Mitochondria Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways			BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Activation of BMF and translocation to mitochondria
Drugs
Diseases
GWAS		Body mass index ( 26865924) Height ( 28552196) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy) ( 28112199) Chronic lymphocytic leukemia ( 28165464 26956414 24292274) Dehydroepiandrosterone sulphate levels ( 21533175) Endometrial cancer ( 30093612 27135401) Endometrial cancer (endometrioid histology) ( 30093612) Endometrial endometrioid carcinoma ( 27135401) Ewing sarcoma ( 22327514) Lung function (FEV1/FVC) ( 30804560) Lung function (FVC) ( 30804560) Lymphocyte counts ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 32888494) Triglyceride levels ( 32203549)
Interacting Genes		5 interacting genes: BMF NTAQ1 PRR3 RIMS3 USP2	26 interacting genes: AQP1 BCL2 BCL2A1 BCL2L1 BCL2L10 BCL2L2 BCL2L2-PABPN1 CTAG1A CTAG1B CXCL9 DYNLL1 DYNLL2 GPSM3 LCN2 MAPK8 MCL1 MGAT5B MYO5A NNMT RECK REL SEC14L4 SHC3 TCF12 TFIP11 TRIM54
Entrez ID		100529063	90427
HPRD ID			05881
Ensembl ID		ENSG00000258643	ENSG00000104081
Uniprot IDs			Q96LC9
PDB IDs
Enriched GO Terms of Interacting Partners?
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