CDH6 and CDH18

Data Source:
HPRD (in vitro, in vivo)

		CDH6	CDH18
Description		cadherin 6	cadherin 18
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Plasma Membrane Adherens Junction Integral Component Of Membrane Catenin Complex Cell Junction	Plasma Membrane Adherens Junction Integral Component Of Membrane Catenin Complex
	Molecular Function	Calcium Ion Binding Cadherin Binding	Calcium Ion Binding Cadherin Binding
	Biological Process	Cell Morphogenesis Cell-cell Junction Assembly Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Notch Signaling Pathway Multicellular Organism Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules	Cell Morphogenesis Cell-cell Junction Assembly Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Multicellular Organism Development Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Adherens Junction Organization Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules
Pathways		Adherens junctions interactions	Adherens junctions interactions
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Cocaine dependence ( 31212010) Disease progression in age-related macular degeneration (adjusted for baseline) ( 29346644) Emphysema-related traits ( 20709820) Gamma glutamyl transferase levels ( 29403010) General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549 28869591) Late-onset myasthenia gravis ( 26562150) Liver enzyme levels (gamma-glutamyl transferase) ( 22001757) Response to lamotrigine and valproic acid in genetic generalized epilepsy ( 32308125) Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Resting heart rate ( 27798624) Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524) Smoking status (ever vs never smokers) ( 30643258) Sweet taste preference ( 32572145)	Childhood body mass index ( 33045005) Depression (quantitative trait) ( 20800221) Diabetes (gestational) ( 31269844) Erectile dysfunction ( 30583798) Metabolic coherence (transcriptomic) ( 30852652) Mitochondrial DNA levels ( 25240745) Obesity in adult survivors of childhood cancer exposed to cranial radiation ( 25963547) Obstetric antiphospholipid syndrome ( 28424481) Resistant hypertension ( 31545351) Response to anti-TNF therapy in rheumatoid arthritis ( 26776603) Serum metabolite concentrations in chronic kidney disease ( 29545352) Type 2 diabetes ( 31049640)
Interacting Genes		5 interacting genes: CDH10 CDH18 CDH19 CDH7 CDH9	4 interacting genes: CDH12 CDH6 CDH9 MYOG
Entrez ID		1004	1016
HPRD ID		04305	04314
Ensembl ID		ENSG00000113361	ENSG00000145526
Uniprot IDs		P55285	D6RER2 Q13634
PDB IDs		5VEB
Enriched GO Terms of Interacting Partners?
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