TIMM23 and TSPAN8

Data Source:
BioGRID (two hybrid)

		TIMM23	TSPAN8
Description		translocase of inner mitochondrial membrane 23	tetraspanin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Mitochondrial Intermembrane Space Integral Component Of Mitochondrial Inner Membrane	Integral Component Of Plasma Membrane Cell Surface Extracellular Exosome
	Molecular Function	Protein Binding Protein Transmembrane Transporter Activity	Integrin Binding Protein Binding
	Biological Process	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix	Spermatogenesis Regulation Of Gene Expression Negative Regulation Of Blood Coagulation
Pathways		Mitochondrial protein import Mitochondrial protein import
Drugs
Diseases
GWAS		Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978) Prostate cancer ( 25939597 27262462)	Asthma ( 32296059) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Medication use (adrenergics, inhalants) ( 31015401) Monobrow ( 27182965) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Type 2 diabetes ( 22885922 18372903 30054458 29358691 30297969 32499647 20581827 28869590) Upper eyelid sagging severity ( 24869959)
Interacting Genes		17 interacting genes: AQP6 CREB3L1 EBP FAM210B FXYD3 GOLT1A HSD17B13 JAGN1 RNASEK SCN3B SLC16A7 TIMM17B TLCD4 TMEM14B TMEM86B TMEM88 TSPAN8	5 interacting genes: PNLIPRP1 PTCH1 SLC38A7 STX2 TIMM23
Entrez ID		100287932	7103
HPRD ID			02865
Ensembl ID		ENSG00000265354	ENSG00000127324
Uniprot IDs		O14925	P19075
PDB IDs
Enriched GO Terms of Interacting Partners?
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