TOMM6 and SLC18A2

Data Source:
BioGRID (two hybrid)

		TOMM6	SLC18A2
Description		translocase of outer mitochondrial membrane 6	solute carrier family 18 member A2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex	Centrosome Plasma Membrane Integral Component Of Plasma Membrane Synaptic Vesicle Membrane Synaptic Vesicle Membrane Terminal Bouton Intracellular Membrane-bounded Organelle Clathrin-sculpted Monoamine Transport Vesicle Membrane Dopaminergic Synapse
	Molecular Function	Protein Binding	Serotonin:sodium Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Protein Transport Macroautophagy	Response To Amphetamine Chemical Synaptic Transmission Neurotransmitter Secretion Locomotory Behavior Response To Toxic Substance Post-embryonic Development Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Dopamine Transport Sequestering Of Neurotransmitter Serotonin Uptake Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways		Mitochondrial protein import PINK1-PRKN Mediated Mitophagy	Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Na+/Cl- dependent neurotransmitter transporters
Drugs			Amphetamine Reserpine Norepinephrine Haloperidol Mazindol Benzphetamine Dopamine Deserpidine Ephedra sinica root MMDA Midomafetamine 4-Methoxyamphetamine Dextroamphetamine Metamfetamine Nomifensine Tetrabenazine Histamine Isometheptene Propylhexedrine Serotonin Rauwolfia serpentina root Deutetrabenazine
Diseases
GWAS			Body mass index ( 26426971) Retinopathy x type 2 diabetes interaction ( 32541925)
Interacting Genes		13 interacting genes: AQP6 C1orf159 CD68 CERS4 ERGIC3 FFAR3 GLP1R ODF4 SEC61A2 SLC10A1 SLC16A2 SLC18A2 TMEM14B	14 interacting genes: BRICD5 CFHR5 CMTM5 CSNK1A1 CSNK2A1 CSNK2A2 CXCR2 DNAJC5 GPR151 MFSD5 NKG7 SLC7A1 TMEM109 TOMM6
Entrez ID		100188893	6571
HPRD ID		19464	01896
Ensembl ID		ENSG00000214736	ENSG00000165646
Uniprot IDs		Q96B49	Q05940
PDB IDs		7CK6
Enriched GO Terms of Interacting Partners?
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