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VEGFC
Description
vascular endothelial growth factor C
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Membrane
Platelet Alpha Granule Lumen
Molecular Function
Vascular Endothelial Growth Factor Receptor Binding
Protein Binding
Growth Factor Activity
Chemoattractant Activity
Vascular Endothelial Growth Factor Receptor 3 Binding
Biological Process
Response To Hypoxia
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Endothelial Cell Proliferation
Sprouting Angiogenesis
Positive Regulation Of Neuroblast Proliferation
Platelet Degranulation
Substrate-dependent Cell Migration
Signal Transduction
Positive Regulation Of Cell Population Proliferation
Animal Organ Morphogenesis
Morphogenesis Of Embryonic Epithelium
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Autophosphorylation
Vascular Endothelial Growth Factor Signaling Pathway
Response To Drug
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Osteoblast Differentiation
Positive Regulation Of Angiogenesis
Negative Regulation Of Blood Pressure
Positive Regulation Of Protein Kinase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Secretion
Positive Chemotaxis
Induction Of Positive Chemotaxis
Positive Regulation Of Cell Division
Positive Regulation Of Mast Cell Chemotaxis
Positive Regulation Of Lymphangiogenesis
Positive Regulation Of Mesenchymal Stem Cell Proliferation
Cellular Response To Leukemia Inhibitory Factor
Pathways
Platelet degranulation
VEGF ligand-receptor interactions
VEGF binds to VEGFR leading to receptor dimerization
Drugs
Diseases
Gastric cancer
GWAS
Blood protein levels (
30072576
29875488
)
Chin dimples (
27182965
)
HIV-1 viral setpoint (
22174851
)
Idiopathic dilated cardiomyopathy (
29495422
)
Intraocular pressure (
29785010
31959993
)
Serum albumin level (
29403010
)
Serum total protein level (
29403010
)
Thyroid stimulating hormone levels (
32769997
)
Interacting Genes
3 interacting genes:
FLT4
KDR
SGTB
Entrez ID
7424
HPRD ID
03317
Ensembl ID
ENSG00000150630
Uniprot IDs
P49767
PDB IDs
2X1W
2X1X
4BSK
Enriched GO Terms of Interacting Partners
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