SYNGAP1

Description		synaptic Ras GTPase activating protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Postsynaptic Density Dendritic Shaft Glutamatergic Synapse
	Molecular Function	GTPase Activator Activity Protein Binding SH3 Domain Binding
	Biological Process	MAPK Cascade Ras Protein Signal Transduction Pattern Specification Process Visual Learning Dendrite Development Receptor Clustering Regulation Of MAPK Cascade Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of GTPase Activity Negative Regulation Of Ras Protein Signal Transduction Regulation Of Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Negative Regulation Of Axonogenesis Regulation Of Synapse Structure Or Activity Maintenance Of Postsynaptic Specialization Structure
Pathways		Regulation of RAS by GAPs
Drugs
Diseases		Non-syndromic autosomal dominant mental retardation
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Late-onset Alzheimer's disease ( 27770636) Schizophrenia ( 30285260)
Interacting Genes		28 interacting genes: CAMK2A DLG3 DLG4 DLGAP4 EFHC1 GRIN1 GRIN2B GRIN2D GUCD1 HSF2BP KDR MGAT5B MID2 MKRN3 MPDZ NCK2 NTAQ1 OSTF1 PDGFRB SPAG8 SUOX TLX3 TRIM27 TRIP6 TSSK3 ULK1 ULK2 VENTX
Entrez ID		8831
HPRD ID		16018
Ensembl ID		ENSG00000197283
Uniprot IDs		A0A1U9X8L0 B7ZCA0 Q96PV0
PDB IDs
Enriched GO Terms of Interacting Partners?
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