SORD

Description		sorbitol dehydrogenase
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GO Annotations	Cellular Component	Extracellular Space Cytosol Membrane Motile Cilium Mitochondrial Membrane Extracellular Exosome
	Molecular Function	(R,R)-butanediol Dehydrogenase Activity L-iditol 2-dehydrogenase Activity Zinc Ion Binding Carbohydrate Binding Identical Protein Binding D-xylulose Reductase Activity Ribitol 2-dehydrogenase Activity NAD Binding
	Biological Process	Glucose Metabolic Process Sorbitol Catabolic Process Response To Osmotic Stress Response To Hormone Glucuronate Catabolic Process To Xylulose 5-phosphate Flagellated Sperm Motility Response To Nutrient Levels Response To Drug Fructose Biosynthetic Process Response To Cadmium Ion Response To Copper Ion L-xylitol Catabolic Process L-xylitol Metabolic Process
Pathways		Fructose biosynthesis Formation of xylulose-5-phosphate
Drugs		NADH Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-Pyrimidine
Diseases
GWAS		Alzheimer's disease in APOE e4+ carriers ( 25778476)
Novel Interacting Genes		1 novel interacting genes: KRT5
Interacting Genes		2 interacting genes: RELA SHBG
Entrez ID		6652
HPRD ID		01679
Ensembl ID		ENSG00000140263
Uniprot IDs		Q00796
PDB IDs		1PL6 1PL7 1PL8
Enriched GO Terms of Interacting Partners?
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