SAV1

Description		salvador family WW domain containing protein 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Cell-cell Junction Dendrite
	Molecular Function	Protein Binding Signaling Receptor Complex Adaptor Activity Beta-1 Adrenergic Receptor Binding Identical Protein Binding SMAD Binding Type II Activin Receptor Binding
	Biological Process	Hair Follicle Development Apoptotic Process Signal Transduction Keratinocyte Differentiation Hippo Signaling Positive Regulation Of Apoptotic Process Receptor Clustering Positive Regulation Of Fat Cell Differentiation Negative Regulation Of Epithelial Cell Proliferation Protein Stabilization Positive Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Cardiac Muscle Cell Proliferation Ventricular Septum Morphogenesis Lung Epithelial Cell Differentiation Intestinal Epithelial Cell Differentiation Regulation Of Stem Cell Population Maintenance
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Dupuytren's disease ( 28886342) Heel bone mineral density ( 30598549) Lupus nephritis in systemic lupus erythematosus ( 24925725) Mean platelet volume ( 32888494 27863252) Periodontal disease-related phenotype (Socransky) ( 24347629) Plasma amyloid beta peptide concentrations (ABx-40) ( 24535457) Platelet count ( 32888494) Platelet distribution width ( 32888494) Refractive error ( 32231278)
Novel Interacting Genes		1 novel interacting genes: POLE2
Interacting Genes		5 interacting genes: EP300 NEDD4 RASSF1 STK3 STK4
Entrez ID		60485
HPRD ID		06229
Ensembl ID		ENSG00000151748
Uniprot IDs		B3KTQ1 Q9H4B6
PDB IDs		6AO5
Enriched GO Terms of Interacting Partners?
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