PNPLA8

Description		patatin like phospholipase domain containing 8
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Membrane Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function	Phospholipase Activity Lysophospholipase Activity ATP Binding Calcium-independent Phospholipase A2 Activity Phosphatidyl Phospholipase B Activity
	Biological Process	Prostaglandin Biosynthetic Process Fatty Acid Metabolic Process Cell Death Arachidonic Acid Metabolic Process Phosphatidylcholine Catabolic Process Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Linoleic Acid Metabolic Process Phosphatidylethanolamine Catabolic Process Arachidonic Acid Secretion Lipid Homeostasis Triglyceride Homeostasis
Pathways		Acyl chain remodelling of PC Acyl chain remodelling of PE
Drugs
Diseases
GWAS		JT interval (sulfonylurea treatment interaction) ( 27958378) Post bronchodilator FEV1/FVC ratio ( 26634245) Smoking behavior ( 22006218) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Novel Interacting Genes		1 novel interacting genes: FLT4
Interacting Genes
Entrez ID		50640
HPRD ID		13741
Ensembl ID		ENSG00000135241
Uniprot IDs		A0A024R746 Q9NP80
PDB IDs
Enriched GO Terms of Interacting Partners?
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