FGF6

Description		fibroblast growth factor 6
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Sarcolemma
	Molecular Function	Fibroblast Growth Factor Receptor Binding Protein Binding Growth Factor Activity
	Biological Process	MAPK Cascade Cartilage Condensation Angiogenesis Positive Regulation Of Protein Phosphorylation Positive Regulation Of Cell Population Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Animal Organ Morphogenesis Positive Regulation Of Gene Expression Cell Differentiation Regulation Of Cell Migration Myoblast Differentiation Positive Regulation Of Cell Division Positive Regulation Of Protein Kinase B Signaling
Pathways		PI3K Cascade PIP3 activates AKT signaling Signaling by activated point mutants of FGFR1 FGFR4 ligand binding and activation FGFR1c ligand binding and activation FGFR2c ligand binding and activation Activated point mutants of FGFR2 Constitutive Signaling by Aberrant PI3K in Cancer Phospholipase C-mediated cascade: FGFR1 Phospholipase C-mediated cascade; FGFR2 Phospholipase C-mediated cascade; FGFR4 Downstream signaling of activated FGFR1 SHC-mediated cascade:FGFR1 PI-3K cascade:FGFR1 FRS-mediated FGFR1 signaling PI-3K cascade:FGFR2 SHC-mediated cascade:FGFR2 FRS-mediated FGFR2 signaling FRS-mediated FGFR4 signaling SHC-mediated cascade:FGFR4 PI-3K cascade:FGFR4 Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Negative regulation of FGFR4 signaling Signaling by FGFR2 in disease Signaling by FGFR1 in disease RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Drugs
Diseases
GWAS		Colorectal cancer ( 23263487) Medication use (antimigraine preparations) ( 31015401) Migraine ( 27182965 27322543) Migraine without aura ( 27322543) Phosphorus levels ( 29403010 20558539) Response to cytadine analogues (cytosine arabinoside) ( 24483146)
Novel Interacting Genes		2 novel interacting genes: CELSR1 KLRC2
Interacting Genes		5 interacting genes: FGFR1 FGFR2 FGFR3 FGFR4 NCALD
Entrez ID		2251
HPRD ID		00623
Ensembl ID		ENSG00000111241
Uniprot IDs		P10767
PDB IDs
Enriched GO Terms of Interacting Partners?
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