DPAGT1

Description		dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
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GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Integral Component Of Endoplasmic Reticulum Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase Activity UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Protein Binding Phospho-N-acetylmuramoyl-pentapeptide-transferase Activity Transferase Activity, Transferring Glycosyl Groups Identical Protein Binding Metal Ion Binding
	Biological Process	UDP-N-acetylglucosamine Metabolic Process Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Dolichyl Diphosphate Biosynthetic Process Dolichol Metabolic Process
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2
Drugs
Diseases		Congenital disorders of glycosylation (CDG) type I
GWAS		Estimated glomerular filtration rate ( 31152163) Lymphocyte percentage of white cells ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Novel Interacting Genes		5 novel interacting genes: CXCR5 ETS1 THTPA TUBE1 WDR5
Interacting Genes		2 interacting genes: LSM8 MFSD3
Entrez ID		1798
HPRD ID		01879
Ensembl ID		ENSG00000172269
Uniprot IDs		A0A024R3H8 Q9H3H5
PDB IDs		5LEV 5O5E 6BW5 6BW6 6FM9 6FWZ 6JQ3
Enriched GO Terms of Interacting Partners?
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