DLST

Description		dihydrolipoamide S-succinyltransferase
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Membrane Centriolar Satellite Oxoglutarate Dehydrogenase Complex
	Molecular Function	Dihydrolipoyllysine-residue Succinyltransferase Activity Protein Binding Transferase Activity, Transferring Acyl Groups
	Biological Process	Generation Of Precursor Metabolites And Energy Tricarboxylic Acid Cycle 2-oxoglutarate Metabolic Process Succinyl-CoA Metabolic Process Lysine Catabolic Process Protein Phosphopantetheinylation L-lysine Catabolic Process To Acetyl-CoA Via Saccharopine Histone Succinylation
Pathways		Glyoxylate metabolism and glycine degradation Lysine catabolism Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS		anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Depression ( 29700475) Eosinophil counts ( 32888494) Mood instability ( 29187730) Non-small cell lung cancer ( 23144319)
Novel Interacting Genes		2 novel interacting genes: ACYP1 ESRRB
Interacting Genes		16 interacting genes: ARIH2 CCDC86 DLG5 FLII NAP1L1 NDRG1 OGDH PAK4 PFN2 RUSC2 SCFD1 TUBB4B UBE2D2 UMPS ZBTB16 ZHX1
Entrez ID		1743
HPRD ID		00520
Ensembl ID		ENSG00000119689
Uniprot IDs		A0A024R6C9 B7Z6J1 P36957
PDB IDs		6H05
Enriched GO Terms of Interacting Partners?
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