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CD79B

Description CD79b molecule
Image
GO Annotations Cellular Component
  • Nucleoplasm
  • Cytosol
  • Plasma Membrane
  • Integral Component Of Plasma Membrane
  • External Side Of Plasma Membrane
  • B Cell Receptor Complex
  • Extracellular Exosome
Molecular Function
  • Transmembrane Signaling Receptor Activity
  • Protein Binding
  • Identical Protein Binding
Biological Process
  • Adaptive Immune Response
  • Immune Response
  • Signal Transduction
  • B Cell Differentiation
  • B Cell Receptor Signaling Pathway
Pathways
  • CD22 mediated BCR regulation
  • Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
  • Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
  • Polatuzumab vedotin
Diseases
  • Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS
  • Height ( 25282103)
Novel Interacting Genes 2 novel interacting genes: FOXJ1 PDZD11
Interacting Genes 14 interacting genes: BLK CD19 CD3E CD5 CD79A FYN LCK LYN PTK2 PTPN6 SGTA SGTB SYK ZAP70
Entrez ID 974
HPRD ID 00922
Ensembl ID ENSG00000007312
Uniprot IDs P40259
PDB IDs 3KG5
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025