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BAP1
Description
BRCA1 associated protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
PR-DUB Complex
Molecular Function
Chromatin Binding
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Peptidase Activity
Cysteine-type Peptidase Activity
Biological Process
Regulation Of Cell Growth
Cellular Protein Modification Process
Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Cell Population Proliferation
Response To Inorganic Substance
Protein Deubiquitination
Protein Phosphopantetheinylation
Monoubiquitinated Protein Deubiquitination
Monoubiquitinated Histone H2A Deubiquitination
Negative Regulation Of Transcription, DNA-templated
Regulation Of Inflammatory Response
Regulation Of Cell Cycle
Macrophage Homeostasis
Protein K48-linked Deubiquitination
Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of Protein Targeting To Mitochondrion
Pathways
UCH proteinases
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
Drugs
Diseases
GWAS
Autism spectrum disorder or schizophrenia (
28540026
)
Bipolar disorder (
21926972
)
Parkinson's disease (
28892059
)
Schizophrenia (
23974872
)
Novel Interacting Genes
2 novel interacting genes:
PARP3
PLN
Interacting Genes
27 interacting genes:
BAG4
BCAR3
BRCA1
CASP8
CBLC
CBX5
ESR1
H2AC18
H2AC20
H2AC4
IGF1R
ITPR3
KLF5
LINC00598
MAP3K1
NBN
PTPRJ
RB1CC1
TRIM63
UBC
UBE2O
USP15
USP2
USP21
USP28
XRCC3
YY1
Entrez ID
8314
HPRD ID
04366
Ensembl ID
ENSG00000163930
Uniprot IDs
A0A024R305
F8W6N3
Q92560
PDB IDs
Enriched GO Terms of Interacting Partners
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