ARHGAP35

Description		Rho GTPase activating protein 35
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GO Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane Actin Cytoskeleton Ciliary Basal Body
	Molecular Function	DNA Binding GTPase Activity GTPase Activator Activity GTP Binding Phospholipid Binding
	Biological Process	Neural Tube Closure Signal Transduction Axon Guidance Axonal Fasciculation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Cell Shape Positive Regulation Of Neuron Projection Development Cell Migration Central Nervous System Neuron Axonogenesis Mammary Gland Development Forebrain Development Establishment Or Maintenance Of Actin Cytoskeleton Polarity Cellular Response To Extracellular Stimulus Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Rho Protein Signal Transduction Camera-type Eye Development Negative Regulation Of Vascular Permeability Positive Regulation Of GTPase Activity Wound Healing, Spreading Of Cells Positive Regulation Of Cilium Assembly Regulation Of Axonogenesis Regulation Of Small GTPase Mediated Signal Transduction Neuron Projection Guidance
Pathways		Rho GTPase cycle Sema4D mediated inhibition of cell attachment and migration PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Deep white matter hyperintensities ( 32517579)
Interacting Genes		6 interacting genes: CDC42 GRB2 KRT31 PTPRZ1 RAC1 SRC
Entrez ID		2909
HPRD ID		05592
Ensembl ID		ENSG00000160007
Uniprot IDs		Q9NRY4
PDB IDs		2K85 3C5H 3FK2 6PXC 6WAY
Enriched GO Terms of Interacting Partners?
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