ALOX5AP

Description		arachidonate 5-lipoxygenase activating protein
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GO Annotations	Cellular Component	Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Nuclear Membrane
	Molecular Function	Glutathione Transferase Activity Leukotriene-C4 Synthase Activity Glutathione Peroxidase Activity Protein Binding Enzyme Activator Activity Protein N-terminus Binding Arachidonic Acid Binding
	Biological Process	Leukotriene Metabolic Process Leukotriene Biosynthetic Process Lipoxygenase Pathway Regulation Of Catalytic Activity Protein Homotrimerization Cellular Response To Calcium Ion Cellular Oxidant Detoxification Lipoxin Biosynthetic Process
Pathways		Synthesis of 5-eicosatetraenoic acids Synthesis of Leukotrienes (LT) and Eoxins (EX) Synthesis of Lipoxins (LX)
Drugs		DG031 AM103 Fiboflapon
Diseases
GWAS		Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU) ( 24025145) General risk tolerance (MTAG) ( 30643258) Non-word repetition ( 23738518)
Novel Interacting Genes		2 novel interacting genes: FLT1 GDF15
Interacting Genes		10 interacting genes: ALOX5 AQP6 CLIC1 FFAR2 GPR42 LTC4S NAPB OPRM1 SLC29A2 TMEM120B
Entrez ID		241
HPRD ID		04742
Ensembl ID		ENSG00000132965
Uniprot IDs		A0A087WW23 P20292
PDB IDs		2Q7M 2Q7R
Enriched GO Terms of Interacting Partners?
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