MFN2

Description		mitofusin 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Cytosol Integral Component Of Membrane Intrinsic Component Of Mitochondrial Outer Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Ubiquitin Protein Ligase Binding
	Biological Process	Protein Targeting To Mitochondrion Apoptotic Process Response To Unfolded Protein Mitochondrial Membrane Organization Cell Cycle Arrest Blood Coagulation Mitochondrial Fusion Macroautophagy Protein Localization To Phagophore Assembly Site Negative Regulation Of Ras Protein Signal Transduction Negative Regulation Of Smooth Muscle Cell Proliferation Mitochondrion Localization Parkin-mediated Stimulation Of Mitophagy In Response To Mitochondrial Depolarization Positive Regulation Of Cold-induced Thermogenesis Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Pathways		PINK1-PRKN Mediated Mitophagy Factors involved in megakaryocyte development and platelet production
Drugs
Diseases		Charcot-Marie-Tooth disease (CMT); Hereditary motor and sensory neuropathy; Peroneal muscular atrophy
GWAS		Inflammatory skin disease ( 25574825) Plasma homocysteine levels ( 30339177) Platelet count ( 22139419 32888494) Plateletcrit ( 32888494) Tuberculosis ( 29036319)
Novel Interacting Genes		1 novel interacting genes: PITRM1
Interacting Genes		2 interacting genes: MARCHF5 PRKN
Entrez ID		9927
HPRD ID		08495
Ensembl ID		ENSG00000116688
Uniprot IDs		O95140
PDB IDs		6JFK 6JFL 6JFM
Enriched GO Terms of Interacting Partners?
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