SH3PXD2A

Description		SH3 and PX domains 2A
Image
GO Annotations	Cellular Component	Podosome Cytoplasm Cytosol Cell Junction Cell Projection
	Molecular Function	Protease Binding Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Phosphatidylinositol-5-phosphate Binding Superoxide-generating NADPH Oxidase Activator Activity Phosphatidylinositol-3,4-bisphosphate Binding Molecular Adaptor Activity Phosphatidylinositol-4-phosphate Binding
	Biological Process	In Utero Embryonic Development Superoxide Metabolic Process Extracellular Matrix Organization Regulation Of Catalytic Activity Osteoclast Fusion
Pathways		Invadopodia formation
Drugs
Diseases
GWAS		Atrial fibrillation ( 28416818 28416822 29290336 29892015) Brain morphology (MOSTest) ( 32665545) Chronic obstructive pulmonary disease or resting heart rate (pleiotropy) ( 30940143) Cutaneous malignant melanoma ( 26237428) Diisocyanate-induced asthma ( 25918132) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Intraocular pressure ( 29617998) Ischemic stroke ( 29531354) Ischemic stroke (small-vessel) ( 29531354) Manganese levels ( 26025379) Periventricular white matter hyperintensities ( 32517579) PR interval ( 30046033 32439900) Refractive error ( 32231278) Rheumatoid arthritis ( 30891314) Stroke ( 29531354) Waist circumference adjusted for body mass index ( 28552196) White matter hyperintensities ( 32358547) White matter hyperintensity burden ( 25663218)
Interacting Genes		7 interacting genes: ADAM15 AFAP1L2 FASLG KHDRBS1 PAK2 SRC SVIL
Entrez ID		9644
HPRD ID		10228
Ensembl ID		ENSG00000107957
Uniprot IDs		B3KPL1 Q5TCZ1
PDB IDs		2DNU 2EGA 2EGC 2EKH
Enriched GO Terms of Interacting Partners?
Tagcloud ?