LGI1

Description		leucine rich glioma inactivated 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space Synaptic Cleft Glutamatergic Synapse
	Molecular Function	Signaling Receptor Binding Protein Binding
	Biological Process	Nervous System Development Axon Guidance Positive Regulation Of Cell Growth Neuron Projection Development Positive Regulation Of Synaptic Transmission Neurotransmitter Receptor Localization To Postsynaptic Specialization Membrane
Pathways		LGI-ADAM interactions
Drugs
Diseases		Autosomal dominant temporal lobe epilepsy (ADTLE); Autosomal dominant partial epilepsy with auditory features (ADPEAF)
GWAS		Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 29274321) Response to (pegylated) interferon in chronic hepatitis B ( 30715261) Response to perphenazine in schizophrenia ( 29503163)
Novel Interacting Genes		1 novel interacting genes: SLC27A2
Interacting Genes		1 interacting genes: ADAM22
Entrez ID		9211
HPRD ID		05216
Ensembl ID		ENSG00000108231
Uniprot IDs		A0A0S2Z4S7 A0A0S2Z4X3 A0A0S2Z5G1 A0A1B0GUD3 O95970
PDB IDs		5Y2Z 5Y30 5Y31
Enriched GO Terms of Interacting Partners?
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